Abstract: FR-PO0408
Neuromuscular Electrical Stimulation as a Treatment for Sarcopenia in People on Haemodialysis (STIM-HD): Collaborative Approach to Impactful and Enduring Research
Session Information
- Dialysis: Measuring and Managing Symptoms and Syndromes
November 07, 2025 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 801 Dialysis: Hemodialysis and Frequent Dialysis
Authors
- Quann, Niamh, University of Leicester, Leicester, England, United Kingdom
- Watson, Emma L., University of Leicester, Leicester, England, United Kingdom
- Burton, James, University of Leicester, Leicester, England, United Kingdom
Background
Chronic Kidney Disease affects 10-12% of adults in the UK, with many requiring haemodialysis. A major challenge for this population is sarcopenia; muscle loss that impacts strength, mobility, and overall wellbeing. While exercise can help, many dialysis patients struggle with fatigue, mobility issues, or simply do not have the energy to engage in traditional exercise. Neuromuscular electrical stimulation (NMES) could be a potential alternative using electrical impulses to activate muscles and mimic the benefits of movement.
Methods
STIM-HD is a multi-centre randomised controlled trial evaluating NMES for improving muscle mass and function in haemodialysis patients. Co-applicants from multiple institutions bring together expertise in nephrology, muscle biology, physiology, rehabilitation, neuromuscular performance, and clinical trials, ensuring a rigorous and multidisciplinary approach. Alongside them, a patient co-applicant with lived experience of kidney failure and dialysis has played a key role in shaping the study. Their input has ensured the study is designed with real-world patient needs in mind; from practical considerations like usability during dialysis, to the importance of giving participants control over their own stimulation settings.
Results
By integrating diverse expertise, collaborating across multiple research centres, and embedding patient leadership, STIM-HD builds trust and creates a sustainable model for patient-centred research. The study does not just test NMES, it also challenges traditional research structures by shifting decision-making power towards participants and fostering long-term collaboration across institutions.
Conclusion
If NMES proves effective, it could transform rehabilitation for haemodialysis patients, offering a practical way to regain muscle strength, improve well-being, and enhance quality of life. More broadly, STIM-HD demonstrates that when researchers, clinicians, and patients collaborate, the outcomes are more meaningful, sustainable, and impactful; not just for this study, but for the future of patient-centred research.
Funding
- Government Support – Non-U.S.