Abstract: SA-PO1100
Body Composition (BC) in Octogenarians with CKD Stages 1-5ND: Role of Gender
Session Information
- Geriatric Nephrology
November 08, 2025 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Geriatric Nephrology
- 1300 Geriatric Nephrology
Authors
- Cigarran, Secundino, Hospital Ribera Polusa, Lugo, Lugo, Spain
- Sanjurjo Amado, Ana Maria, Hospital Publico da Mariña, Burela, Lugo, Spain
- Vázquez Rodríguez, Raquel, Hospital Ribera Polusa, Lugo, Lugo, Spain
- Santidrián Novo, Amaia, Hospital Ribera Polusa, Lugo, Lugo, Spain
- Rios, Jose, Hospital Clinic de Barcelona, Barcelona, Barcelona, Spain
- Gonzalez-Parra, Emilio E., Fundación Jimenez Díaz, Madrid, Madrid, Spain
- Barril, Guillermina, Instituto Fundaciones Biomedicas, Madrid, Madrid, Spain
Background
The aging global population is rising CKD prevalence.BC changes are frequent in octogenarians, often intensifying negative effects. Data on CKD prevalence and BC clinical significance are limited. This study evaluates BC differences in octogenarians within a Nephrology Unit over 14 years, focusing on gender.
Methods
724 included (34.1%) of 2126 pts,335 women, 46.4%, age 84.7 ± 3.5 years, 42.1% diabetics underwent bioimpedance BIVA (Akern, Modena, Italy). Measurements Na-K exchange, Body Cell Mass (BCM), Muscle Mass (MM), Fat Mass (FM), Total Body Water (TBW), Intracellular Water (ICW), Extracellular Water (ECW), and Phase Angle (PhA).Muscle strength assessed with Handgrip Dynamometer (NexGen Ergonomics Inc, Quebec, Canada).Additionally, risk factors for RRT evaluated with the KFRE equation,fracture risk FRAX, and comorbidity with Charlson's age-adjusted algorithm. Data analyzed with SPSS 28.Significance P<0.05
Results
Epidemiologically, women exhibited lower comorbidity and risk of onset of RRT, but higher risk of osteoporotic fractures. BC, women had a higher % Fat 42.1±6.9 vs 31.8±6.9; p <0.001 and ECW% 52.6±6.02vs50.8±5.5;p <0.001,lower MM% 33.0±6.9 vs.39.4±7.12;P<0.001 and Na-K ex 1.08±0.2vs1.16±0.2;p <0.001.[Fig1] Females also showed lower muscle strength (16.5±4.9vs 26.1±7.4;p <0.001).Dynapenia was more common in men (27%) compared to women (20.4%).5.7% of patients exhibiting sarcopenia.
Conclusion
Gender differs BC of octogenarians with CKD.Male have a high functional performance than women.Thus, tailored management therapies are essential to slow disease progression and improve quality of life. With the rising life expectancy, kidney transplantation could be a viable option for eligible patients.
Funding
- Private Foundation Support