Abstract: FR-PO0561
Body Roundness Index on the Clinical Outcome of Patients on Peritoneal Dialysis: Analysis of Two Cohorts
Session Information
- Home Dialysis: Clinical Epidemiology
November 07, 2025 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 802 Dialysis: Home Dialysis and Peritoneal Dialysis
Authors
- Szeto, Cheuk-Chun, The Chinese University of Hong Kong, Hong Kong, Hong Kong
- Xu, Lixing, The Chinese University of Hong Kong, Hong Kong, Hong Kong
- Ng, Jack Kit-Chung, The Chinese University of Hong Kong, Hong Kong, Hong Kong
Background
Central obesity is common among patients undergoing peritoneal dialysis (PD) and may have important metabolic consequences. The Body Roundness Index (BRI) is a convenient anthropometric measurement that represents central adiposity and visceral fat. However, its prognostic value in PD patients has not yet been explored.
Methods
We conducted a retrospective study involving two cohorts of PD patients: an exploratory cohort of 249 prevalent PD patients and a validation cohort of 162 incident ones. In addition to BRI, we performed bioimpedance spectroscopy and other routine clinical and biochemical tests. Outcome measures included patient survival, technique survival, peritonitis-free survival, and hospitalization rates.
Results
In the exploratory cohort, the baseline BRI was an independent risk factor for all-cause mortality, with an adjusted hazard ratio of 1.346 (95% CI: 1.094 to 1.655, p = 0.005), and for technique failure, with an adjusted hazard ratio of 1.279 (95% CI: 1.079 to 1.517, p = 0.004). A high BRI was also associated with a higher frequency of hospitalizations (p = 0.001) and longer hospital stays (p = 0.002). In the validation cohort, baseline BRI was also associated with patient survival by univariate Cox regression analysis, but the result became insignificant after adjusting for confounding clinical factors by multi-variable Cox regression.
Conclusion
A high BRI is associated with increased rates of all-cause mortality and hospitalization. However, the results from the exploratory and validation cohorts were somewhat inconsistent, indicating the necessity for further research to validate our findings.