Kidney Week

Abstract: FR-PO1055

Effect of Prior Kidney Transplant on Contrast-Induced Nephropathy Following Coronary Angiography

Session Information

• Transplantation: Clinical - Pharmacology and Nonkidney Solid Organ Transplants
  November 07, 2025 | Location: Exhibit Hall, Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: Transplantation

• 2102 Transplantation: Clinical

Authors

• Kato, Mariko, Resilience Healthcare - Weiss Memorial Hospital LLC, Chicago, Illinois, United States

Mariko Kato, MD

• Tran, Viet Nghi, Resilience Healthcare - Weiss Memorial Hospital LLC, Chicago, Illinois, United States

Viet Nghi Tran, MD

• Dhital, Roman, Resilience Healthcare - Weiss Memorial Hospital LLC, Chicago, Illinois, United States

Roman Dhital, MD

• Tang, Yunjing, Resilience Healthcare - Weiss Memorial Hospital LLC, Chicago, Illinois, United States

Yunjing Tang, MD

• Luo, Linjie, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Linjie Luo, MD

• Waqar, Danish, Resilience Healthcare - Weiss Memorial Hospital LLC, Chicago, Illinois, United States

Danish Waqar, MBBS

Background

Contrast induced nephropathy (CIN) is a common complication of coronary angiography, particularly in patients with impaired renal function. Kidney transplant recipients may be at increased risk for CIN, but current evidence remains limited. This study investigated the impact of prior kidney transplant on the risk of CIN following coronary angiography.

Methods

A retrospective cohort study was performed utilizing the National Inpatient Sample database from 2017 to 2021. Adult patients who underwent coronary angiography during hospitalization were included and categorized based on history of kidney transplant. Propensity score matching and multivariate logistic regression were used to assess the association between prior kidney transplant and the risk of developing CIN. Subgroup analyses were conducted separately among patients who underwent coronary angiography alone and those who underwent coronary angiography with stent placement.

Results

Among a total of 5,266,630 admissions meeting the study criteria, 15,845 patients (0.30%) had a history of kidney transplant. The odds of developing CIN were not statistically higher among patients with a history of kidney transplant compared to those without (post-matching OR 1.17, 95% CI 0.78-1.75, p=0.452). In the subgroup analysis, the odds of developing CIN following coronary angiography alone were not significantly different (aOR 1.47, 95% CI 0.93-2.32, p=0.095). However, among patients having stent placement, the odds of developing CIN were higher in the transplant group (aOR 1.51, 95% CI 1.03-2.20, p=0.035).

Conclusion

Prior kidney transplant was not associated with an elevated risk of developing CIN following coronary angiography alone, but was associated with a higher risk of CIN in patients having stent placement. Further randomized trials are needed to clarify this association.

The odds of developing CIN following coronary angiography with stent placement were significantly higher in the transplant group.

Digital Object Identifier (DOI)

• doi: 10.1681/ASN.2025vxasbjbk