Abstract: FR-PO0416
Prognostic Value of Snack Intake Patterns in Patients on Maintenance Hemodialysis
Session Information
- Dialysis: Measuring and Managing Symptoms and Syndromes
November 07, 2025 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 801 Dialysis: Hemodialysis and Frequent Dialysis
Author
- Liu, Tong, Zhongshan Hospital Fudan University, Shanghai, Shanghai, China
Background
To explore the predictive value of snack intake patterns for hyperphosphatemia and major adverse cardiovascular events (MACE) in maintenance hemodialysis (MHD) patients.
Methods
Snack questionnaire data was collected from 99 MHD patients at Shanghai Geriatric Medical Center. Patients were classified into low-(<5 times), medium-(<10 times), and high-frequency(>10 times) snack intake groups based on their weekly snacking habits. The most important variables were screened by randomized survival forest (RSF) which were included in the Cox regression model. The primary endpoint was the composite endpoint of hyperphosphatemia and MACE.
Results
(1) Kaplan- Meier curves revealed a lower risk of composite endpoint events in the low-frequency group.
(2)The RSF analysis screened out the six most important variables.
Conclusion
Snack intake more than 10 times weekly represents an independent risk factor for the development of hyperphosphatemia and MACE in MHD patients.
Cox proportional hazards regression modeling of composite endpoints
| Model | Crude model | Model 1 | Model 2 | Model 3 | ||||
| HR(95%CI) | p | HR(95%CI) | p | HR(95%CI) | p | HR(95%CI) | p | |
| Medium- | 2.1 (1.2,3.6) | 0.01 | 1.85 (3.02,3.4) | 0.04 | 2.22 (0.68,7.3) | 0.18 | 2.31 (0.71,7.5) | 0.17 |
| High- | 5.6 (2,16) | 0 | 4.49 (1.5,13.4) | 0.01 | 5.57 (1.17,26.6) | 0.03 | 5.45 (1.17,25.4) | 0.03 |
The low frequency group was used as a reference. Crude model: uncorrected. Model 1: corrected for age, sex, BMI; Model 2: corrected for age, sex, BMI, snack type; Model 3: corrected for age, sex, BMI, snack type, phosphorus binding agent.
Funding
- Private Foundation Support