Abstract: FR-PO0407
Physical Activity Fragmentation in Patients on Hemodialysis: Results from a Prospective Observational Study
Session Information
- Dialysis: Measuring and Managing Symptoms and Syndromes
November 07, 2025 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 801 Dialysis: Hemodialysis and Frequent Dialysis
Authors
- Han, Maggie, Fresenius Medical Care, New York, New York, United States
- Malhotra, Rakesh, University of California San Diego, San Diego, California, United States
- Tao, Xia, Renal Research Institute, New York, New York, United States
- Preciado, Priscila, Renal Research Institute, New York, New York, United States
- Tisdale, Lela, Fresenius Medical Care, New York, New York, United States
- Thwin, Ohnmar, Renal Research Institute, New York, New York, United States
- Kotanko, Peter, Renal Research Institute, New York, New York, United States
Background
Fragmentation of physical activity may indicate poor physical functioning and potential clinical decline. This study aims to evaluate the degree of physical activity fragmentation in a cohort of in-center hemodialysis patients.
Methods
HD patients from 4 New York City clinics were enrolled starting in June 2018 and followed for up to 1 year. Ambulatory patients ≥18 years, on maintenance HD, and owning a mobile device were included. Each patient was provided with and taught how to use a wearable activity tracker (Fitbit Charge 2®), and they were instructed to wear the device continuously. Minute-by-minute activity data over the entire observation period were used to categorize each minute as either active (≥10 steps/minute) or sedentary. Only physical activity data from 05:00 to 23:00 was extracted to exclude sleep periods. We extracted features including activity fragmentation (ratio of active segments to total active minutes*100), and three categories of activity bouts (<5, 5-10, and ≥10 consecutive active minutes).
Results
79 HD patients (54±11 years, 63% Black, 75% male, 34% diabetic were included in our analysis. Median and mean±SD activity fragmentation was 47% (IQR 40 – 54%) and 48±11%. The mean percent of time spent in activity bouts of <5 min, 5-10 min, and >=10 min was 90%, 8%, and 2%, respectively. Distribution of physical activity fragmentation can be seen in Figure 1.
Conclusion
HD patients have highly fragmented physical activity patterns. The association between activity fragmentation and outcomes should be further investigated.
Funding
- Commercial Support – Renal Research Institute