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Abstract: FR-PO0995

Enhancing Donor Recovery and Intensive Care Unit (ICU) Efficiency with a Donor Care Unit

Session Information

Category: Transplantation

  • 2102 Transplantation: Clinical

Authors

  • Farhat, Souha, Houston Methodist Hospital, Houston, Texas, United States
  • Ibarra, Sergio H., LifeGift Organ Donation Center, Houston, Texas, United States
  • Powley, Nicole, LifeGift Organ Donation Center, Houston, Texas, United States
  • Browning, Ivy Kristine, LifeGift Organ Donation Center, Houston, Texas, United States
  • Ambroise, Woodlhey C, LifeGift Organ Donation Center, Houston, Texas, United States
  • Potter, Thomas B, Houston Methodist Hospital, Houston, Texas, United States
  • Meinders, Andrea M., Houston Methodist Hospital, Houston, Texas, United States
  • Al Awadhi, Solaf, Houston Methodist Hospital, Houston, Texas, United States
  • Waterman, Amy D., Houston Methodist Hospital, Houston, Texas, United States
  • Axelrod, David, University Hospitals, Cleveland, Ohio, United States
  • Cooper, Matthew, Medical College of Wisconsin, Milwaukee, Wisconsin, United States
  • Becker, Yolanda T, LifeGift Organ Donation Center, Houston, Texas, United States
  • Myer, Kevin A., LifeGift Organ Donation Center, Houston, Texas, United States
  • Woodside, Kenneth J., Sharing Hope SC, Charleston, South Carolina, United States
Background

This study assessed the early impact of a regional Donor Care Unit (DCU) on donor management, ICU resource use, and transplant outcomes.

Methods

This is a retrospective study of 340 adult donors managed by LifeGift (07/2022 - 12/2024) at a tertiary center with an ICU-based DCU. All met neurologic death and UNOS eligibility. Primary outcome was organs transplanted per donor; secondary outcomes included donor management goal (DMG) attainment and ICU time savings. Statistical tests included Chi-squared, Wilcoxon Rank-Sum, and logistic regression.

Results

Organ recovery/transplantation rates were higher among DCU donors. Donors transferred to the DCU had higher DMG attainment (mean 7.00 vs. 5.93; p<0.001), with 69.6% meeting ≥7 DMGs compared to 41.4% of non-DCU donors (p<0.001). DCU transfer resulted in a median ICU time savings of 35.9 hours (p<0.001). In multivariable analysis, DCU transfer independently predicted optimal donor management (aOR 3.56 [1.80–6.24]; p<0.001).

Conclusion

A regional DCU improved DMG achievement, reduced ICU resource utilization, and increased organ recovery rates. These findings support the integration of specialized donor management units to optimize organ donation processes.

Digital Object Identifier (DOI)