Abstract: TH-PO0999
Racial Disparities in Post-Kidney Transplant Outcomes: Focus on Graft Failure, Rejection, Infection, and Related Complications
Session Information
- Diversity and Equity in Kidney Health
November 06, 2025 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Diversity and Equity in Kidney Health
- 900 Diversity and Equity in Kidney Health
Authors
- Mansoor, Sobia, Landmark Medical Center, Woonsocket, Rhode Island, United States
- Agrawal, Siddharth, Landmark Medical Center, Woonsocket, Rhode Island, United States
- Tated, Ritu Chandra Prakash, New York Medical College, Valhalla, New York, United States
- Soni, Kriti, SUNY Upstate Medical University, Syracuse, New York, United States
- Jain, Hritvik, All India Institute of Medical Sciences Jodhpur, Jodhpur, RJ, India
- Shah, Radhe Kinner, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
- Monsour, Michael J., Landmark Medical Center, Woonsocket, Rhode Island, United States
Background
Kidney transplantation remains the optimal treatment for ESRD, providing enhanced survival and quality of life relative to dialysis. Nonetheless, considerable racial & ethnic differences endure in transplant accessibility, graft longevity, and post-transplant outcomes. This study aims to assess racial inequalities in significant kidney transplant complications, including graft failure, rejection, infection, & other adverse events, within a diverse national sample.
Methods
A retrospective study of 612,178 kidney transplant hospitalizations (2016–2022) assessed racial disparities in failure, infection, & rejection using 95% confidence intervals. Patient demographics, comorbidities, hospital characteristics, length of stay, and total charges were also analyzed.
Results
Among 612,178 kidney transplant hospitalizations from 2016 to 2021, significant racial disparities were observed in post-transplant complications (p < 0.001).Hispanic patients had significantly lower odds of transplant failure (OR 0.746, p < 0.001) and rejection (OR 0.64, p < 0.001) compared to White patients. In contrast, Black (OR 1.14, p = 0.009) and Native American (OR 1.86, p = 0.002) patients had significantly higher odds of rejection. The odds of experiencing other renal transplant complications were significantly higher in Black (OR 2.13, p < 0.001), Native American (OR 2.23, p = 0.001), and Hispanic (OR 1.51, p = 0.007) patients.
Conclusion
Racial disparities in kidney transplant outcomes persist, with Black and Native American patients at higher risk of rejection and complications. In contrast, Hispanic patients had more favorable outcomes. Targeted interventions are needed to address these inequities and improve transplant care for all.