Abstract: FR-PO0452
Association Between Risk of Obstructive Sleep Apnea and Cardiovascular Disease in Patients with ESKD
Session Information
- Dialysis: Measuring and Managing Symptoms and Syndromes
November 07, 2025 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 801 Dialysis: Hemodialysis and Frequent Dialysis
Authors
- Moon, Sung Jin, Catholic Kwandong University International Saint Mary's Hospital, Incheon, Korea (the Republic of)
- Chang, Jae Hyun, Gachon University Gil Medical Center, Incheon, Korea (the Republic of)
- Koh, Hee Byung, Yonsei University Health System, Seoul, Korea (the Republic of)
Background
This study aims to investigate the relationship between the STOP-BANG score, which quantifies the risk of obstructive sleep apnea (OSA), and the prevalence of cardiovascular disease (CVD)s in hemodialysis patients.
Methods
This cross-sectional study included patients aged ≥18 years with kidney failure undergoing hemodialysis, recruited from the hemodialysis unit of a tertiary hospital in August 2023. The STOP-BANG score, assessed using an eight-item questionnaire, was categorized into three groups: low (0–2), moderate (3–4), and severe (5–8 or meeting specific criteria for severe risk). The primary outcomes were the prevalence of CVDs, including ischemic heart disease, ischemic stroke, hemorrhagic stroke, atrial fibrillation, and heart failure, as identified through ICD-10 and OPCS-4 codes.
Results
Among the 130 participants (median age: 62.9 years; male: 53.8%), the prevalence of CVDs was as follows: ischemic heart disease (36.9%), ischemic stroke (19.2%), hemorrhagic stroke (4.6%), AF (23.8%), and heart failure (33.1%). In multivariate logistic regression analysis for ischemic stroke, the adjusted odds ratio (adj-OR) per unit increase in STOP-BANG score was 2.11 (95% CI: 1.37–3.23, P = 0.001)[Table 1]. Patients in the high-risk OSA group had significantly higher odds of ischemic stroke (adj-OR: 9.71, 95% CI: 1.10–85.95, P = 0.041). For atrial fibrillation, the adj-OR per unit increase in STOP-BANG score was 1.82 (95% CI: 1.21–2.75, P = 0.004). High-risk OSA patients also had significantly increased odds of AF (adj-OR: 5.79, 95% CI: 1.03–32.55, P = 0.046). There were no significant associations with ischemic heart disease, hemorrhagic stroke, and heart failure.
Conclusion
A higher STOP-BANG score, indicating increased OSA risk, was significantly associated with ischemic stroke and atrial fibrillation in hemodialysis patients. Identifying high-risk patients using the STOP-BANG score can aid in screening and may help guide interventions, such as CPAP therapy, to reduce cardiovascular risk.
Table 1.