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Abstract: SA-PO0406

A Novel Helical Peritoneal Dialysis Catheter

Session Information

Category: Dialysis

  • 802 Dialysis: Home Dialysis and Peritoneal Dialysis

Authors

  • Sathik, Nafees R, Northeast Ohio Medical University, Rootstown, Ohio, United States
  • Grden, Adam R, Northeast Ohio Medical University, Rootstown, Ohio, United States
  • Parashar, Sameer, Northeast Ohio Medical University, Rootstown, Ohio, United States
  • Raina, Rupesh, Akron Children's Hospital, Akron, Ohio, United States
Background

Peritoneal dialysis (PD) is a cost effective method for kidney replacement therapy; however, the catheters have not been innovated upon since the 1970s. Common complications of PD catheters include port clogging due to fibrin deposition and omentum wrapping. We developed a novel catheter (NEOFlow) to decrease complications due to decreased flow rate.

Methods

NEOFlow is a novel 8F Y-shaped helical catheter with helices of 25.4 mm diameter, helices peaks 12.7 mm apart, and 60 ports on the inner lumen of each helix (Fig 1). For testing, we utilized a peritoneum simulation environment consisting of a resealable plastic bag and 1 quart of water, wrapped around a blood pressure cuff exerting 15 mmHg (Fig. 2). We compared flow rates by measuring water flow over 30-seconds and the flow of an egg/vinegar mixture to simulate fibrin deposition (25mL egg white/yolk mix, 5mL vinegar) through each catheter over 30-seconds. Each test was run 5 times.

Results

NEOFlow significant increased flow vs the coiled catheter (14.7% , p = 0.001). Additionally, NEOFlow had a significant increase in flow vs the control during the fibrin deposition simulation (18.0%, p = 0.0028) (Table 1). Finally, visual inspection of both catheters showed less protein deposition on NEOFlow.

Conclusion

Our novel PD catheter, NEOFlow, had statistically significant differences in flow rate compared to existing coil catheters. These results support the further development and testing of our device to translate it for clinical application.

Percent comparisons of catheters
Comparison% Difference in Flow rate
Coiled → Y-Shaped (Control)+14.66%*
Coiled → Y-Shaped (Clotting)+17.96%*
Coiled → Coiled w/ Clotting-9.67%*
Y-Shaped → Y-Shaped w/ Clotting-7.07%*

* indicates statistically significant results

Digital Object Identifier (DOI)