Abstract: PUB371
Psychological Distress and Cardiovascular-Kidney-Metabolic (CKM) Syndrome Among US Hispanic/Latino Adults
Session Information
Category: CKD (Non-Dialysis)
- 2301 CKD (Non-Dialysis): Epidemiology, Risk Factors, and Prevention
Authors
- Larkin, Claire T., University of Illinois Chicago, Chicago, Illinois, United States
- Ashrafi, Sadia Anjum, University of Illinois Chicago, Chicago, Illinois, United States
- Sotres-Alvarez, Daniela, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States
- Rosas, Carlos E., San Diego State University, San Diego, California, United States
- Hernandez, Rosalba, University of Illinois Chicago, Chicago, Illinois, United States
- Elfassy, Tali, University of Miami, Coral Gables, Florida, United States
- Lash, James P., University of Illinois Chicago, Chicago, Illinois, United States
Background
CKM conceptualizes clustering of risk factors including metabolic disorders, CKD, and cardiovascular disease (CVD). The influence of psychological health on CKM is unknown. The purpose of this study is to evaluate the association of psychological distress with severity of CKM stage among diverse US Hispanic/Latino adults.
Methods
The Hispanic Community Health Study/Study of Latinos is a population-based cohort of Hispanics/Latino adults aged 18-74 years from four US cities. This cross-sectional study included 14,760 participants who completed a comprehensive exam. Predictors: depressive symptoms (assessed using the CES-D 10, ≥10 indicates depressive symptoms) and anxiety (evaluated using the Spielberger Trait Anxiety Short Form, STAI-10, ≥20 indicates elevated anxiety).Outcome: CKM stage: Stage 0 (no risk factors), Stage 1 (excess adiposity), Stage 2 (metabolic risk factors and CKD), Stage 3 (subclinical CVD), and Stage 4 (clinical CVD). Multivariable logistic regression used to estimate prevalence ratios for association between psychological distress measures and advanced CKM (stage 3 or 4) vs. nonadvanced (stages 0, 1, or 2) accounting for complex survey design.
Results
Mean age was 46 years and 60% were female, 27% had depressive symptoms and 28% had elevated anxiety symptoms. Individuals with depressive symptoms had a higher prevalence of CKM stage 3 and 4; and those with elevated anxiety had a higher prevalence of CKM stage 4 (Table). Prevalence ratios adjusted for age, sex, and education are shown in Figure.
Conclusion
Measures of psychosocial distress were associated with more advanced stages of CKM. Future work is needed to understand these relationships and to develop targeted interventions to improve outcomes for patients with CKM syndrome.
Funding
- Other NIH Support