Abstract: PUB097
Pre- and Post-Serum Calcium Levels in Online Postdilution Hemodiafiltration
Session Information
Category: Dialysis
- 801 Dialysis: Hemodialysis and Frequent Dialysis
Authors
- Wagner, Carolina Steller, Nefrostar Kidney Care, Sao Paulo, Brazil
- Resende, Larissa, Nefrostar Kidney Care, Sao Paulo, Brazil
- Batista, Lucileide, Nefrostar Kidney Care, Sao Paulo, Brazil
- Quilelli, Amanda L, Nefrostar Kidney Care, Sao Paulo, Brazil
- Magalhães, Andréa Olivares, Nefrostar Kidney Care, Sao Paulo, Brazil
- Kojima, Christiane, Nefrostar Kidney Care, Sao Paulo, Brazil
- Rocha, Érica Pires da, Nefrostar Kidney Care, Sao Paulo, Brazil
- Cuppari, Lilian, Nefrostar Kidney Care, Sao Paulo, Brazil
- Elias, Rosilene M., Nefrostar Kidney Care, Sao Paulo, Brazil
Background
Post-dilution hemodiafiltration (OL-HDF) may lead to a negative calcium balance. However, studies have shown that switching from low-flux hemodialysis to OL-HDF does not significantly alter serum calcium levels. We evaluated pre- and post-dialysis serum calcium levels in patients on maintenance OL-HDF.
Methods
This cross-sectional, multicenter study aimed to evaluate pre- and post-dialysis calcium levels in patients receiving maintenance post-dilution OL-HDF. Data from all consecutive HDF sessions over the course of one week were included.
Results
A total of 79 patients (60.8% male, 44% on conventional, 49.4% on short-daily, and 6.3% on long nocturnal OL-HDF) were included in the study. Pre- and post-dialysis calcium levels from all consecutive sessions are shown in Table 1. All but 4 patients had an increase in calcium levels from pre- to post-OL-HDF. The change in calcium levels was dependent on dialysate calcium concentration (higher with dialysate calcium concentrations equal to or greater than 1.5 mEq/L) and pre-dialysis serum calcium. The frequency and duration of sessions had no effect on the calcium change.
Conclusion
Our study shows that OL-HDF significantly alters calcium levels. The change in calcium levels was primarily influenced by the dialysate calcium concentration and pre-dialysis serum calcium, rather than session frequency or duration. This is crucial information for managing patients on long-term hemodialysis.
Mean (SD) of calcium levels
| Ca levels, md/dL | Session 1 | Session 2 | Session 3 | Session 4 | Session 5 | Session 6 |
| Pre OL-HDF | 8.9 (0.8) | 9.0 (0.7) | 9.1 (0.6) | 9.3 (0.6) | 9.3 (0.6) | 9.4 (0.7) |
| Post OL-HDF | 10.2 (0.8) | 10.2 (0.7) | 10.3 (0.7) | 10.3 (0.7) | 10.3 (0.7) | 10.3 (0.7) |
| Post dialysis maximim value | 12.2 | 11.8 | 11.9 | 12.0 | 11.7 | 11.8 |