Abstract: PUB245
A Serious Case of Renal Tubular Acidosis in a Young Female Patient with Sjogren Syndrome
Session Information
Category: Glomerular Diseases
- 1402 Glomerular Diseases: Clinical, Outcomes, and Therapeutics
Authors
- Park, Hae Sang, G Sam Hospital, Gyeonggi, Gunpo, Korea (the Republic of)
- Kwon, Young-Joo, Korea University Guro Hospital, Seoul, Gurogu, Korea (the Republic of)
Introduction
Sjogren's syndrome is an autoimmune disease characterized by dry mouth and dry eyes due to decreased saliva and tear secretion due to lymphocyte infiltration of exocrine glands that secrete fluids outside the body. We report a severe case of a young woman aged 30 years .
Case Description
The patient was a 30-year-old female patient who visited the emergency room the day before with symptoms of extreme weakness. The potassium level was 1.2 mEq/L, showing severe hypokalemia, and HCO3- showed about 13 mEq/L of metabolic acidosis. More surprisingly, multiple fractures were confirmed in the sternum, ribs of both rib cage , sacrum , cervical spine and pelvic bone. Severe osteoporosis was confirmed with a T score of -5.4 in the L spine.
In addition, the patient showed macroscopic hematuria , and a CT abdomen scan was performed, which revealed a large number of stones filling the bladder and multiple calyceal stones . The stones were removed through urological surgery . Ultimately, the patient was diagnosed with type 1 RTA (renal tubular acidosis)based on the test results and symptoms. A salivary gland biopsy was performed, and Sjogren’s syndrome was diagnosed. The patient's ANA and anti-Ro, anti-La antibodies were positive.
Discussion
n the case of the patient, hypokalemia and acidosis could be recovered through treatment for more than a year due to the severity of symptoms and test results. In addition, osteoporosis and multiple fractures were severe, and there were many stones. It is meaningful to report this case because it was an extremely severe case at a young age of 30.