Abstract: PUB289
Trends and Disparities in Hypertensive Kidney Disease- and Chronic Obstructive Pulmonary Disease-Related Mortality in the United States. 1999-2023
Session Information
Category: Hypertension and CVD
- 1602 Hypertension and CVD: Clinical
Authors
- Ali, Muhammad, Dow International Medical College, Karachi, Sindh, Pakistan
- Nasir, Anas, Sheikh Zayed Medical College, Rahim Yar Khan, Punjab, Pakistan
- Hussain, Dania, United Medical and Dental College, Karachi, Sindh, Pakistan
- Waseem, Neha, FMH College of Medicine and Dentistry, Lahore, Punjab, Pakistan
- Ghafur, Sadia, United Medical and Dental College, Karachi, Sindh, Pakistan
- Zahid, Muhammad Saad, Foundation University Medical College, Islamabad, Islamabad Capital Territory, Pakistan
- Khan, Ahmed Ali, Foundation University Medical College, Islamabad, Islamabad Capital Territory, Pakistan
- Imran, Haider, Foundation University Medical College, Islamabad, Islamabad Capital Territory, Pakistan
- Ali, Irtiza, Texas A&M University, College Station, Texas, United States
Background
Hypertensive Renal Disease (HRD) and Chronic Obstructive Pulmonary Disease (COPD) are interlinked, and research is limited concerning their shared mortality trends in the United States. We analyze HRD and COPD-related mortality in adults aged 65 and older from 1999 to 2023, with an added focus on demographic and geographic factors.
Methods
The CDC WONDER Multiple Cause-of-Death Public Use records from 1999 to 2023 were used to analyze mortality trends amongst adults ≥65 years using ICD-10 codes for HRD (I12) and COPD (J40, J41, J42, J43, J44). Age-adjusted mortality rates (AAMR) per 100,000 people, along with annual percent change (APC) and average annual percent change (AAPC), were stratified by year, along with demographic and regional subgroups using Joinpoint regression software.
Results
90,677 HRD and COPD-related deaths occurred from 1999 to 2023, mainly in the decedent’s home (34.04%). Overall, AAMR rose from 1.7 in 1999 to 18.5 in 2023. Disparities in mortality rates among different demographic and regional distributions were noted. AAMR increased the most in women (AAPC: 12.6; 95%CI: 9.9 to 15.5), non-Hispanic Whites (AAPC: 12.5; 95%CI: 9.9 to 15.4), the Midwest (AAPC: 12.2; 95%CI: 9.6 to 15.2), and rural areas (AAPC: 13.9; 95%CI: 10.9 to 17.2). California had the highest percentage of deaths at 11.46%.
Conclusion
HRD and COPD-related mortality in the United States from 1999-2023 is increasing, with significant disparities amongst demographic and regional distributions. Early intervention strategies and policy changes are important to improve mortality rates in at-risk communities.