Abstract: SA-PO1224
Trends in Viral/Bacterial Pneumonia and CKD-Related Mortality in the United States, 1999-2023
Session Information
- CKD: Biomarkers and Emerging Tools for Diagnosis and Monitoring
November 08, 2025 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: CKD (Non-Dialysis)
- 2302 CKD (Non-Dialysis): Clinical, Outcomes, and Trials
Authors
- Ali, Muhammad, Dow International Medical College, Karachi, Sindh, Pakistan
- Ahmad, Wajdan, Al-Tibri Medical College, Karachi, Sindh, Pakistan
- Nasir, Anas, Sheikh Zayed Medical College, Rahim Yar Khan, Punjab, Pakistan
- Hussain, Dania, United Medical and Dental College, Karachi, Sindh, Pakistan
- Imran, Haider, Foundation University Medical College, Islamabad, Islamabad Capital Territory, Pakistan
- Fatima, Maryam, Foundation University Medical College, Islamabad, Islamabad Capital Territory, Pakistan
- Ramzan, Ahsan, Sheikh Zayed Medical College, Rahim Yar Khan, Punjab, Pakistan
- Haque, Zahra Ali, Riphah International University Islamic International Medical College, Rawalpindi, Punjab, Pakistan
- Ali, Irtiza, Texas A&M University, College Station, Texas, United States
Background
Research into viral/bacterial pneumonia and chronic kidney disease (CKD)- related mortality is paramount, as these are 2 common and interlinked diseases. This study aims to explore the mortality-related trends and disparities associated with these conditions from 1999 to 2023 in the United States.
Methods
The CDC WONDER Multiple Cause-of-Death Public Use records from 1999 to 2023 were used to analyze mortality trends amongst adults ≥65 years using ICD-10 codes for viral and bacterial pneumonia (J10-J18) and CKD (N18). Age-adjusted mortality rates (AAMRs) per 100,000 people, along with annual percent change (APC) and average annual percent change (AAPC), were stratified by year, along with demographic and regional subgroups using Joinpoint regression software.
Results
145,493 viral/bacterial pneumonia and CKD-related deaths occurred from 1999 to 2023, mainly occurring in medical facilities (74.8%). Overall, AAMR rose from 11.1 in 1999 to 13.1 in 2023. AAMR increased in women (AAPC: 2.2; 95%CI: 0.7 to 4.1), contrasting with relatively stable values for men throughout the study duration. Racially, all groups experienced relatively stable values in terms of AAPC throughout. Regionally, the Northeast had increasing AAMR compared to other regions, which had stability throughout (AAPC Northeast: 1.4; 95%CI: 0.01 to 2.9). Metropolitan and nonmetropolitan areas had increasing AAMR (AAPC metro: 2.3; 95%CI: 0.6 to 3.7, AAPC nonmetro: 3.0; 95%CI: 1.0 to 4.4).
Conclusion
Viral/bacterial pneumonia and chronic kidney disease (CKD)-related mortality is on the rise with distinct demographic and geographic disparities. This underscores the urgent need for additional research to address these inequalities and reduce the growing mortality rates. The increase in deaths during 2019 and beyond may be linked to the impacts of COVID-19.