Abstract: FR-PO0064
Contrast-Associated Kidney Injury After Percutaneous Coronary Intervention at Kaiser Permanente East Bay Hospitals: A Quality Improvement Project During the Early COVID-19 Pandemic
Session Information
- AKI: Epidemiology, Risk Factors, and Prevention
November 07, 2025 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Acute Kidney Injury
- 101 AKI: Epidemiology, Risk Factors, and Prevention
Authors
- Shah, Rahimeen, University of California Berkeley, Berkeley, California, United States
- Shah, Ahmed Ijaz, The Permanente Medical Group Inc, Oakland, California, United States
- Zheng, Sijie, The Permanente Medical Group Inc, Oakland, California, United States
Background
Contrast-associated acute kidney injury (AKI) following percutaneous coronary interventions (PCI) can result in chronic renal dysfunction. Our quality improvement project examined the incidence of AKI a year before and after the onset of the COVID-19 pandemic and its association with contrast volume used.
Methods
This quality improvement project utilized hospital databases to identify patients undergoing PCI, their baseline comorbidities, contrast volume used, pre- and post-PCI serum creatinine, and need for new dialysis between 1/1/19-12/31/21. We excluded patients with diagnostic angiography without PCI. AKI was defined as an increase in serum creatinine of ≥ 0.3 mg/dL or ≥ 50% from baseline or new dialysis during hospital stay. Crude and risk-adjusted AKI incidences were compared with national average rates published in the database maintained by the American College of Cardiology. We used Chi-square tests to compare annual incidence rates and multivariable logistic regression to evaluate risk factors for AKI.
Results
A total of 892 PCI procedures in 829 unique patients were identified. The yearly annual incidence of new AKI was 6.4%, 10.0%, and 11.5%, respectively, showing an increasing trend over time (p=0.04). The unadjusted incidence of AKI was 9.2% (95% CI: 7.3-11.1%), the local risk-adjusted rate from the ACC was 7.9% (95% CI: 6.2-9.6%). This matched the reported national incidence of 7.9%. First-time dialysis occurred in 0.3% of patients, with AKI more common in females (15.0% vs 8.0% in males) and in those with hypertension, prior MI, heart failure, diabetes, or previous PCI. No significant difference was found in contrast volume between AKI vs non-AKI procedures (145 mL vs 154 mL, both below the 203 mL national average), and AKI incidence remained stable before and after the pandemic onset.
Conclusion
Our findings align with the increasing national trend of AKI incidence post-PCI. However, there is no significant difference between the local KP East Bay incidence and the national average. The average contrast used per PCI procedure was found to be 50 mL lower than the national average, with no significant impact of contrast volume used on AKI incidence. We found no significant increase in AKI trend in the year following the COVID-19 pandemic compared to the year prior.