Abstract: SA-PO1165
Frequency of Heart Failure in Hyperkalemia Among Patients with CKD in Mexico City
Session Information
- CKD: SGLT2 Inhibitors and GLP-1 RAs for Kidney Health
November 08, 2025 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: CKD (Non-Dialysis)
- 2302 CKD (Non-Dialysis): Clinical, Outcomes, and Trials
Authors
- Hernandez-Garcia, Leslie Nahomi, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, CDMX, Mexico
- Filardo-Zuniga, Marimar, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, CDMX, Mexico
- Arvizu Hernández, Mauricio, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, CDMX, Mexico
Group or Team Name
- Cardionephrology.
Background
Hyperkalemia is a frequent electrolyte imbalance in patients with chronic kidney disease (CKD) and heart failure and is associated with adverse cardiovascular outcomes. However, the frequency of hyperkalemia in HF patients within CKD populations in Latin America remains understudied.
Methods
A retrospective observational study was conducted during the months of December 2024 to April 2025 in patients who attended for outpatient evaluation by nephrology at a tertiary care hospital in Mexico City. Clinical and laboratory data were collected from electronic medical records. Hyperkalemia was defined as serum potassium >5.1 mmol/L. HF diagnosis was confirmed through documented clinical assessment.
Results
Among the 305 patients, the mean age of the population was 49 years (SD ±16.6). 106 (34.7%) had a diagnosis of HF on medical records. Of these, 66 (62.2%) exhibited hyperkalemia. In the non-HF group (n=199), hyperkalemia was observed in 120 patients (60.3%). Most of the episodes of hyperkalemia occurred in ambulatory patients (72.7%), and 27.2% were hospitalized. Left ventricular ejection fraction (LVEF) was preserved in 72% of HF patients based on available echocardiographic data. Valvular abnormalities were common among HF patients (78.9%), particularly mitral and tricuspid insufficiency.
Conclusion
Hyperkalemia was highly prevalent in CKD patients, both with and without HF, with a slightly higher frequency among those with HF. These findings underscore the importance of routine potassium monitoring in CKD populations due to its potential role in worsening cardiac function.