Abstract: FR-PO0381
Association of Blood Pressure Patterns with Loss of Residual Uresis in Patients on Dialysis at the Valentín Gómez Farías Regional Hospital
Session Information
- Hypertension and CVD: Clinical - 2
November 07, 2025 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Hypertension and CVD
- 1602 Hypertension and CVD: Clinical
Authors
- Robles Garcia, Francisco, Universidad de Guadalajara, Guadalajara, Jal., Mexico
- Mendoza Villalobos, Edna Teresa, Universidad de Guadalajara, Guadalajara, Jal., Mexico
- Breien Alcaraz, Hugo Sergio, Universidad de Guadalajara, Guadalajara, Jal., Mexico
- Anaya, Juan Carlos, Universidad de Guadalajara, Guadalajara, Jal., Mexico
- Sanchez, Alejandra, Universidad de Guadalajara, Guadalajara, Jal., Mexico
- Saavedra, Maria Fernanda, Universidad de Guadalajara, Guadalajara, Jal., Mexico
- Villagómez Garcia, Citlally Montserrat, Universidad de Guadalajara, Guadalajara, Jal., Mexico
- Quintero Solis, Rodrigo, Universidad de Guadalajara, Guadalajara, Jal., Mexico
Background
Residual kidney function is a key predictor of survival and quality of life in chronic kidney disease on dialysis therapy, and is associated with improved fluid management, nutrition, and cardiovascular control. Hypertension affects 60–90% of these patients. Circadian blood pressure patterns (dipping, nondipping, and reversal) are associated with organ damage and cardiovascular risk, although their association with loss of residual uresis is understudied.
Methods
Ambispective cross-sectional, analytical study in elderly patients with Chronic Kidney Disease on dialysis and pre-dialysis, in whom a blood pressure pattern was documented by ABPM. The ANOVA test was used for analysis of variance of residual uresis over time, and the Tukey/Bonferroni test was used for comparisons between different blood pressure patterns. Statistical significance was considered at a p value <0.05.
Results
Time showed a significant impact on the loss of residual urine output (p < 0.001), with a time-circadian pattern interaction (p = 0.019). Between-group differences: No significant differences at specific time points (ANOVA: p = 0.743 at baseline, 0.271 at 6 months, 0.102 at 12 months); progressive divergence was observed (Eta2: 0.016 → 0.075). The Reverse Dipper group showed greater absolute loss at 12 months (−586 ml/day), while the Reverse Dipper group showed relative stability (+42 ml/day at 6 months). Post hoc: Multiple comparisons (Tukey/Bonferroni) did not identify significant differences (p > 0.40).
Conclusion
There is a significant impact on the loss of residual diuresis in dialysis patients, showing that the Reverse Dipper group presented greater absolute loss at 12 months compared to other patterns. The beneficial impact of preserving residual uresis is well known, so it is important to know all the factors that may impact its maintenance, one of them being the determination of the blood pressure profile and its association with the preservation of residual uresis.