Kidney Week

Abstract: FR-PO0438

Clinical Findings in Patients Diagnosed with Infective Endocarditis in a Hemodialysis Unit in Mexico

Session Information

• Dialysis: Measuring and Managing Symptoms and Syndromes
  November 07, 2025 | Location: Exhibit Hall, Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: Dialysis

• 801 Dialysis: Hemodialysis and Frequent Dialysis

Authors

• Santisbais Beas, Maria del Refugio, Centro Medico Nacional del Occidente, Guadalajara, Jal., Mexico

Maria del Refugio Santisbais Beas, MEd

• Barbosa, Jonathan, Centro Medico Nacional del Occidente, Guadalajara, Jal., Mexico

Jonathan Barbosa, MD

• Muñoz Montes de Oca, Diana Laura, Centro Medico Nacional del Occidente, Guadalajara, Jal., Mexico

Diana Laura Muñoz Montes de Oca

• Alcala, José Gilberto, Centro Medico Nacional del Occidente, Guadalajara, Jal., Mexico

José Gilberto Alcala, DrMed

• Cruz Landino, Moises, Centro Medico Nacional del Occidente, Guadalajara, Jal., Mexico

Moises Cruz Landino, MD

• Parra Guerra, Ricardo, Centro Medico Nacional del Occidente, Guadalajara, Jal., Mexico

Ricardo Parra Guerra, MD

• Banda Lopez, Adriana, Centro Medico Nacional del Occidente, Guadalajara, Jal., Mexico

Adriana Banda Lopez, MD

Group or Team Name

• Departamento de Nefrologia y Trasplante, Centro Médico Nacional de Occidente, IMSS, Guadalajara Jalisco.

Background

Infective endocarditis (IE) in hemodialysis (HD) patients is associated with high morbidity and mortality. Despite its clinical relevance, data on IE in HD patients in Mexico is limited. The aim of this study was to determine the frequency of IE in chronic kidney disease(CKD) patients on HD

Methods

Retrospective, single-center study of 88 adult HD patients diagnosed with IE (native/prosthetic valve) based on modified Duke criteria, hospitalized between Dec 2021 - Dec 2023. Clinical, microbiological, and echocardiographic data were collected at diagnosis; patient mortality was assessed at discharge

Results

Of the 163 CKD patients on HD admitted during the study period, 88 were diagnosed with IE (48.9% female, 51.1% male). Hypertension was the most common comorbidity (n=54, 61.4%), followed by diabetes (n=32, 36.4%) and atrial fibrillation (n=1, 1.1%). Bacteremia was present at diagnosis in 84 patients (95%). The most frequent vascular access type was non-tunneled catheter (n=52, 59.1%). The average vegetation length was 1.9 ± 0.87cm. Cardiac surgery was performed in 51 patients (58%). Fig. 1 and Table 1 present the frequency of pathogens associated with IE and valvular involvement. Hospital mortality was reported in 34 patients (38%)

Conclusion

IE is a life-threatening complication in HD patients. High rates of bacteremia and non-tunneled catheter use were observed. The tricuspid valve was most frequently involved in this cohort, unlike other series where the mitral valve predominated. Improved vascular access strategies and early detection are key to reduce mortality

Digital Object Identifier (DOI)

• doi: 10.1681/ASN.2025wt00p9x0