Abstract: SA-PO0784
Epidemiology of Glomerular Diseases and Biopsy Sample Quality: Nephrology vs. Interventional Radiology (IR) at a Secondary Hospital in Mexico City
Session Information
- Glomerular Research: Design, Registries, Surveys, and Epidemiology
November 08, 2025 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Glomerular Diseases
- 1402 Glomerular Diseases: Clinical, Outcomes, and Therapeutics
Authors
- Mora Lojan, Jose Luis, Hospital General Dr Manuel Gea Gonzalez, Mexico City, CDMX, Mexico
- Reyes Torres, Bruno Eduardo, Hospital General Dr Manuel Gea Gonzalez, Mexico City, CDMX, Mexico
- Martínez Cuautle, Jimena, Hospital General Dr Manuel Gea Gonzalez, Mexico City, CDMX, Mexico
- Juarez, Joana Balderas, Hospital General Dr Manuel Gea Gonzalez, Mexico City, CDMX, Mexico
- Salinas-Ramirez, Mauricio Adrian, Hospital General Dr Manuel Gea Gonzalez, Mexico City, CDMX, Mexico
- Hernández Castillo, José Luis, Hospital General Dr Manuel Gea Gonzalez, Mexico City, CDMX, Mexico
- Diaz Garcia, Juan Daniel, Hospital General Dr Manuel Gea Gonzalez, Mexico City, CDMX, Mexico
Background
Glomerular diseases represent a diverse group of conditions affecting the glomerulus and adjacent structures through various primary or secondary mechanisms. Kidney biopsy remains the diagnostic gold standard, allowing identification of key histopathological changes. This study analyzes the epidemiology in a secondary-level hospital and compares sample quality between nephrology and interventional radiology services.
Methods
A retrospective descriptive study was conducted on patients who underwent percutaneous kidney biopsy at a secondary-level hospital in Mexico City between January 2017 and December 2024. Clinical and demographic data were collected, including age, sex, and presumptive diagnosis, as well as procedural variables such as sample quality, histopathological findings, and the performing service (nephrology or interventional radiology).
Results
The mean age was 39.9 ± 13.8 years in the IR group and 38.9 ± 15.2 years in the NEPH group, with no statistically significant difference (p = 0.672). The proportion of males was 54.5% in IR compared to 37.0% in NEPH (p = 0.180). The average number of cores was higher in the IR group (1.73 ± 0.67) compared to NEPH (1.37 ± 0.49), showing a statistically significant difference (p = 0.037). The number of glomeruli was similar between groups (IR: 15.4 ± 7.0; NEPH: 15.1 ± 7.6), with no significant difference (p = 0.958). Optimal samples were obtained in 90.9% of IR cases and 81.5% of NEPH cases (p = 0.289). The most frequent diagnoses were lupus nephritis (11.7%), IgA nephropathy (8.3%), and membranous nephropathy (8.3%).
Conclusion
A high proportion of optimal percutaneous kidney biopsy samples was obtained by both services, with no statistically significant differences in patient age, sex distribution, or number of glomeruli. The interventional radiology group yielded a greater number of cores per procedure. The most common diagnoses were lupus nephritis, IgA nephropathy, and membranous nephropathy.