Abstract: TH-PO1202
Reduction in Peritonitis-Related Hospitalization and Catheter Loss with the CloudCath Remote Monitoring System
Session Information
- Late-Breaking Research Posters
November 06, 2025 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 802 Dialysis: Home Dialysis and Peritoneal Dialysis
Authors
- Williamson, Don E., GastroKlenz Inc, San Francisco, California, United States
- Yu, Eric Hsiang, GastroKlenz Inc, San Francisco, California, United States
- ElBadry, Aly, GastroKlenz Inc, San Francisco, California, United States
- Chertow, Glenn M., Stanford University School of Medicine, Stanford, California, United States
Background
Peritonitis remains the leading cause of technique failure for peritoneal dialysis. Results from the CATCH study (Mehrotra et al. Kidney Int Rep 2024) demonstrated that the CloudCath Remote Monitoring System could reliably detect turbidity consistent with peritonitis a median of 3 days earlier than current standard of care. In CATCH, turbidity data was not shared with patients or care providers. Earlier detection should improve clinical outcomes, including fewer hospitalizations, and improved cure rates, represented by a reduced number of catheter removals.
Methods
Prospective, multicenter open-label trial conducted in 228 patients receiving peritoneal dialysis and using the Cloudcath Remote Monitoring System (with feedback) over 56,212 days (154 patient-years). Primary endpoints were peritonitis-related hospitalization and PD catheter loss due to peritonitis. Interim analysis was conducted at end of Q2 2025 using the previously published CATCH study as the comparator. Differences in hospitalization and catheter loss were compared between the treatment and control (CATCH study) groups with two-sided chi-square tests. Relative risks with 95% confidence intervals (95% CI) were calculated by the normal approximation method.
Results
Patients using the CloudCath Remote Monitoring System experienced a 45% (95% CI 14–64%) lower risk of peritonitis-related hospitalization (p=0.0079) and a 56% (95% CI 11–78%) lower risk of peritoneal dialysis catheter loss (p=0.023) relative to standard of care surveillance.
Conclusion
Our real-world evidence and ongoing clinical experience with the CloudCath system indicates its use in PD offers clinically meaningful and statistically significant reductions in the likelihood of peritonitis-related hospitalization and peritoneal dialysis catheter loss.
Funding
- Commercial Support – Cloudcath