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Abstract: TH-PO1079

Housing Insecurity and Risk of Kidney Disease in an Urban Population

Session Information

Category: CKD (Non-Dialysis)

  • 1901 CKD (Non-Dialysis): Epidemiology, Risk Factors, and Prevention


  • Novick, Tessa Kimberly, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States
  • Han, Dingfen, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States
  • Zonderman, Alan B., Intramural Research Program, NIA, NIH, Baltimore, Maryland, United States
  • Evans, Michele Kim, National Institutes of Health/National Institute on Aging, Baltimore, Maryland, United States
  • Crews, Deidra C., Johns Hopkins University School of Medicine, Baltimore, Maryland, United States

Housing insecurity is characterized by high housing costs or unsafe living conditions that prevent general self-care and threaten independence. It is associated with decreased healthcare access, and increased risk for chronic diseases and medical complications. The objective of this study was to examine the association between housing insecurity, incident chronic kidney disease (CKD) and rapid kidney function decline.


Data from the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study (Baltimore, MD) was used for this longitudinal analysis. Housing insecurity was defined as answering yes to the question, “Can you afford a suitable home?” at the HANDLS wave 3 visit. We used multivariable logistic regression to compare risk of rapid kidney function decline (loss of > 5ml/min/1.73m2 eGFR per year over a median of 3.5 years), incident reduced eGFR (< 60 ml/min/1.73m2) and incident albuminuria (albumin-creatinine ratio [ACR] > 30mg/g), between participants with and without housing insecurity.


Of the 1354 HANDLS participants included, mean age was 48 years, 40% were male and 57% were African American. A total of 443 (32.7%) were housing insecure. After a median of 3.5 years follow up, rapid kidney function decline, incident reduced eGFR and incident albuminuria occurred in 213 (15.7%), 68 (5.2%) and 80 (6.6%) participants respectively. After multivariable adjustment, housing insecurity was associated with increased odds of incident albuminuria but there were no statistically significant associations between housing insecurity and rapid kidney function decline or incident reduced kidney function (Table).


Housing insecurity was associated with increased risk for incident albuminuria in an urban population. The prevalence of housing insecurity among persons with CKD and its impact on kidney outcomes is worthy of further study.


  • Other NIH Support