Abstract: TH-PO456
Prevalence of Abdominal Aortic Calcifications in CKD Patients in the Arabian Gulf Region
Session Information
- Hypertension and CVD: Epidemiology, Risk Factors, Prevention
October 25, 2018 | Location: Exhibit Hall, San Diego Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Hypertension and CVD
- 1401 Hypertension and CVD: Epidemiology, Risk Factors, and Prevention
Authors
- AlSahow, Ali, Jahra Hospital, Jahra, Kuwait
- Al-Ali, Fadwa S., Hamad Hospital, Doha, Qatar
- El Essawy, Basset, Ibrahim Bin Hamad Obaidallah Hospital, Ras AlKhaimah, United Arab Emirates
- Al Yousef, Anas M., Farwaniya Hospital, Sabah AlNaser, Kuwait
- Husain, Mohamed Nowrooz, Salmanyia Hospital, Manama, Bahrain
Background
Abdominal aortic calcification (AAC) is an important risk factor for cardiovascular disease (CVD). CVD is the commones complication of chronic kidney disease (CKD). In the Arabian Gulf, few studies were conducted on CKD patients. Aim was to determine AAC prevalence in dialysis and non-dialysis CKD patients and determine relevant predictive factors.
Methods
We performed a multi-center, multi-national chart review of 546 adult CKD patients who have had a plain abdominal x-ray within 6 months prior to study entry. We collected data about patients’ demographics, CKD stage, medical history and comorbidities, lipid profile, current medications and reviewed X-rays for AAC presence.
Results
A total of 544 CKD patients were eligible for analysis including 325 (59.7%) dialysis patients and 219 (40.3%) non-dialysis patients. 290 (53.3%) patients were males and 369 (67.8%) were diabetics. Mean age was 57.98 years (SD ± 15.39). Table 1 describes the distribution of patients according to CKD stage and AAC prevalence in each stage. Overall, AAC was reported in 203 (37.3%, 95% CI=33.2%: 41.4%) patients. AAC prevalence among dialysis patients (126 patients, 38.8%) did not differ significantly from that among non-dialysis patients (77 patients, 35.2%) (p=0.393). Higher risk of AAC development was associated with age, as mean age for AAC group was 66 for non AAC group was 53 (p< 0.001); diabetes, as 45.3% of diabetics developed AAC, compared to 20.6% of non-diabetics developing AAC (p< 0.001), with diabetic patients 2.1 times more likely to have AAC than non-diabetic patients; and longer dialysis vintage, which was 1.92 years in AAC group compared to 1.18 years in non AAC group (p= 0.003). Gender, hypertension and CVD had no associations with AAC.
Conclusion
Our study shows that AAC is present in more than one third of CKD patients in the Arabian Gulf. Risk is higher with older age, diabetes, and longer dialysis vintage.
AAC Prevalence
| CKD Stage | Number of patients | Patients with AAC |
| Non Dialysis | 219 40.3% of all | 77 35.2% of non dialysis |
| CKD 2 | 29 13.2% % of non dialysis | 5 17.2% % of Corresponding CKD stage |
| CKD 3 | 81 37% | 33 40.7% |
| CKD 4 | 45 24.7% | 22 40.7% |
| CKD 5 | 55 25.1% | 17 30.9% |
| Dialysis | 325 59.7% of total | 126 38.8% of all dialysis |
| Total | 544 | 203 37.3% of total |
Funding
- Commercial Support –