ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

learn more

Contact ASN

1401 H St, NW, Ste 900, Washington, DC 20005


The Latest on Twitter

Kidney Week

Abstract: TH-PO171

Epidemiology and Prognostic Importance of Atrial Fibrillation in Kidney Transplant (KT): A Meta-Analysis

Session Information

Category: Transplantation

  • 1802 Transplantation: Clinical


  • Khoury, Nadeen J., Henry Ford Health, Detroit, Michigan, United States
  • Thongprayoon, Charat, Bassett Medical Center, Cooperstown, New York, United States
  • Bathini, Tarun J., Bassett medical center, Cooperstown, New York, United States
  • Chokesuwattanaskul, Ronpichai, King Chulalongkorn Memorial Hospital, Lansing, Michigan, United States
  • Cheungpasitporn, Wisit, University of Mississippi, Mississippi, Mississippi, United States

This meta-analysis was conducted with aims to summarize all available evidence on prevalence of pre-existing atrial fibrillation (AF) and/or incidence of AF following kidney transplantation and the outcomes of KT recipients with AF.


A literature search was conducted utilizing MEDLINE, EMBASE and Cochrane Database from inception through March 2018. We included studies that reported 1) prevalence of pre-existing AF or incidence of AF following kidney transplantation or 2) outcomes of KT recipients with AF. Effect estimates from the individual study were extracted and combined utilizing random-effect, generic inverse variance method of DerSimonian and Laird. The protocol for this meta-analysis is registered with PROSPERO (International Prospective Register of Systematic Reviews; no. CRD42018086192).


8 cohort studies with 137,709 kidney transplant recipients were enrolled. Overall, the pooled estimated prevalence of pre-existing AF in patients undergoing kidney transplantation was 7.0% (95%CI: 5.6%-8.8%) and pooled estimated incidence of AF following kidney transplantation was 4.9% (95%CI: 1.7%-13.0%). Meta-regression analyses were performed and showed no significant correlations between year of study and either prevalence of pre-existing AF (p =0.93) or post-operative AF after kidney transplantation (p =0.16). The pooled OR of mortality among KT recipients with AF was 1.86 (3 studies; 95%CI: 1.03-3.35). In addition, AF is also associated with death-censored allograft loss (2 studies; OR: 1.55, 95%CI: 1.02-2.35) and stroke (3 studies; OR: 2.54, 95%CI: 1.11-5.78) among KT recipients.


The overall estimated incidence of AF following kidney transplantation is 4.9%. Despite advances in medicine, incidence of AF following KT doesn't seem to decrease over time. In addition, there is a significant association of AF with increased mortality, allograft loss, and stroke after kidney transplantation.