Kidney Week

Abstract: TH-PO308

Intradialytic Activities and Health-Related Quality of Life

Session Information

• Dialysis: Cost, Socioeconomics, Quality of Life
  October 25, 2018 | Location: Exhibit Hall, San Diego Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: Dialysis

• 701 Dialysis: Hemodialysis and Frequent Dialysis

Authors

• Warsame, Fatima M., Johns Hopkins University, Baltimore, Maryland, United States

Fatima M. Warsame,

• Ying, Hao, Johns Hopkins School of Medicine, Baltimore, Maryland, United States

Hao Ying,

• Haugen, Christine E., Johns Hopkins Hospital , Baltimore, Maryland, United States

Christine E. Haugen,

• Thomas, Alvin G., UNC Chapel HIll, Chapel Hill, North Carolina, United States

Alvin G. Thomas,

• Crews, Deidra C., Johns Hopkins University School of Medicine, Baltimore, Maryland, United States

Deidra C. Crews,

• Shafi, Tariq, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States

Tariq Shafi,

• Jaar, Bernard G., Johns Hopkins University and Nephrology Center of Maryland, Baltimore, Maryland, United States

Bernard G. Jaar,

• Segev, Dorry L., Johns Hopkins University, Baltimore, Maryland, United States

Dorry L. Segev,

• McAdams-DeMarco, Mara, Johns Hopkins, Baltimore, Maryland, United States

Mara McAdams-DeMarco,

Background

Given the time burden and physiologic effects of hemodialysis, patients who spend dialysis time physically or intellectually engaged may have better health-related quality of life (HRQOL). We sought to characterize the association between intradialytic activities and HRQOL and explore patients' interest in performing intradialytic interventions.

Methods

In a prospective cohort study of 431 prevalent hemodialysis patients, an activity score was assigned on a scale of 0-5 points for each active intradialytic task (read, electronic games, puzzles, chat, other-physical/cognitive). We quantified the association between KDQOL components and activity using adjusted linear regression.

Results

The two most common intradialytic activities reported by patients were passive [watching TV (87.9%) and sleeping (72.4%)]. Patients who were female (aOR=1.85, 95%CI:1.28, 2.66; p=0.001), nonfrail (aOR=1.70, 95%CI:1.06-2.70; p=0.03), and nonsmokers (aOR=2.61, 95%CI:1.39, 4.90; p=0.003) had a higher intradialytic activity. Additionally, higher intradialytic activity was associated with better mental HRQOL (+0.83 points, 95%CI: +0.04, +1.62; p=0.04) and kidney disease-specific HRQOL (+1.70 points, 95%CI: +0.47, +2.93; p=0.007), but not physical HRQOL. Each one-point increase in the activity index was associated with a 1.29-fold and 1.25-fold increased odds of interest in intradialytic cognitive training and physical exercise.

Conclusion

Hemodialysis patients with more active intradialytic activities report better mental and kidney disease-specific HRQOL and increased interest in participating in intradialytic interventions. Dialysis providers may consider offering patients with low levels of activity additional support and opportunities to engage in beneficial intradialytic activities.

Funding

• NIDDK Support