Abstract: FR-PO1152
Observational Descriptive Analysis from the Korean Pediatric CKD Registry
Session Information
- Pediatric Nephrology - I
October 26, 2018 | Location: Exhibit Hall, San Diego Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Pediatric Nephrology
- 1600 Pediatric Nephrology
Authors
- Ahn, Yo Han, Seoul National University Bundang Hospital, Seongnam, Korea (the Republic of)
- Choi, Hyun Jin, Seoul National University Children's Hospital, Seoul, Korea (the Republic of)
- Jang, KyungMi, Yeungnam University School of Medicine and Yeungnam University hospital, Daegu, Korea (the Republic of)
- Yang, Eun mi, Chonnam National University Medical School, Gwangju, Korea (the Republic of)
- Han, Kyoung Hee, Jeju National University School of Medicine, Jeju, Korea (the Republic of)
- Kim, Seong heon, Pusan National University Children's Hospital, Yangsan, Korea (the Republic of)
- Suh, Jin-Soon, Bucheon St.Mary's Hospital, Catholic University, Bucheon, Korea (the Republic of)
- Cho, Heeyeon, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea (the Republic of)
- Cho, Min Hyun, Kyungpook National University, School of Medicine, Daegu, Korea (the Republic of)
- Shin, Jae Il, Yonsei University College of Medicine, Severance Children's Hospital, Seoul, Korea (the Republic of)
- Lee, Joo Hoon, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea (the Republic of)
- Kang, Hee Gyung, Seoul National University Children's Hospital, Seoul, Korea (the Republic of)
- Namgoong, Meekyung, Wonju Severance Christian Hospital, Wonju, Korea (the Republic of)
- Park, Young seo, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea (the Republic of)
- Cheong, Hae Il, Seoul National University Children's Hospital, Seoul, Korea (the Republic of)
- Ha, IL-Soo, Seoul National University Children's Hospital, Seoul, Korea (the Republic of)
Background
The prevalence of chronic kidney disease (CKD) has increased over the last decades. Nevertheless, there still are limited data on epidemiology of childhood CKD in Korea. To improve the understanding and management of Korean pediatric patients with CKD, we established the Korean Pediatric CKD Registry in 2004. We aimed to assess the incidence and prevalence of end stage renal disease (ESRD), etiology, renal replacement therapy (RRT) modalities in children with CKD.
Methods
From January 2004 to December 2016, 713 patients <20 years of age with CKD have been registered in the Korean Pediatric CKD Registry. Demographic and clinical data were collected from 16 centers. Updating of the data was done at least once a year. We analyzed patients who started RRT before the age of 20 years.
Results
Among 713 enrolled patients, 442 patents developed end stage renal disease at mean age of 9.8±5.4 years. The age distribution was as follows: <5 years 21.0%, 5-9 years 27.1%, 10-14 years 33.0%, and 18.8% were >15 years. The main causes of ESRD were glomerulopathy (40.7%) and congenital anomalies of kidney and urinary tract (CAKUT, 24.8%). Glomerulopathy predominated in females, while CAKUT was the majority among males. The annual incidence of ESRD had increased from 1.75 per million age-related populations (pmarp) in 2004 to 2.58 pmarp in 2016. The point prevalence of ESRD was 2.38 pmarp in 2004, and 4.67 pmarp in 2016. The first modality of RRT was peritoneal dialysis in 240 (54.3%), hemodialysis in 118 (26.7%), and preemptive kidney transplantation in 84 (19.0%) patients. Pre-emptive kidney transplantation was more common in older age group (5.1% in age of 0 to <5 years and 28.9% in age of 15 to <20 years).
Conclusion
This study provided the epidemiologic profile of Korean pediatric patients with ESRD. The number of pediatric patients with ESRD had steadily increased. Peritoneal dialysis was the preferred method of RRT for children in Korea.