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Abstract: TH-PO401

Significant Decrease in PD Peritonitis Rate Using FMC Multiple Tubing Segment Set with Stay Safe Pin Technology Compared to Baxter MiniCap Extended Life PD Transfer Set

Session Information

Category: Dialysis

  • 703 Dialysis: Peritoneal Dialysis

Authors

  • Alappan, Harish Raj, Emory University - Undergraduate, Atlanta, Georgia, United States
  • Thompson, Jennifer, Davita, Columbus, Georgia, United States
  • Alappan, Raj, Renal Associates, LLC, Columbus, Georgia, United States
Background

Peritoneal Dialysis Peritonitis (PDP) is a common and serious complication of Peritoneal Dialysis (PD) resulting in structural & functional alteration in membrane function and membrane failure. Reporting PDP rates varies by country. As of 2016, ISPD recommends a rate < 0.5 episodes/year at risk. Any measures to reduce PDP rate is of utmost importance. We analyzed our PDP data retrospectively, comparing Baxter to FMC transfer sets for PDP. Our center has one of the lowest PDP rates compared to ISPD’s 2016 PDP recommendation.

Methods

PD data from Davita Home Dialysis Center, Columbus GA was retrospectively analyzed from Aug. 2013 to Dec. 2017. During this period a total of 111 PD patient data was available for analysis. Baxter transfer sets were used initially from Aug. 2013, and then transitioned to FMC transfer set from 2016 onwards. During this period (53 months) there were 39 PDP episodes; of these 32 were single episode. PDP rate per year and per month was calculated for overall study group and between Baxter and FMC Sets.

Results

Total of 111 patients, mean age is 57.82 ± 1.89 yrs, 68(61%) male, 66 (59.5%) used Baxter & 45(40.5%) used FMC transfer set. Mean BMI was 32.15, nPR 0.727, Albumin 3.41 g/dL, HB 10.25 g/dL, PTH 465.93, with a mean K+ of 4.35 mmol/dL. 21 PDP episodes (53.8%) were due to Staph species. For a total of 159.67 PD years, overall PDP rate in the cohort was 0.244/year, and 1 PDP in every 4.304 years or 1 in every 51.65 months. First PDP occurred at a mean of 465.2 days from the start of PD. Baxter patient had higher KTV at 2.101 ± 0.11, versus FMC 1.746 ± 0.11 (p=0.035).

Conclusion

Data from our center indicates our PDP rate is significantly lower in comparison to ISPD data, suggesting both Baxter and FMC transfer sets are equally effective in achieving such a low PDP rate. Baxter’s higher KTV rate correlates to higher PDP rate. Between the two, the FMC transfer set was more effective in reducing PDP, with the lowest rate and more delayed occurrence of PDP. We recommend a large prospective study to validate our data.