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Abstract: TH-PO452

Relationship Between Ankle Brachial Blood Index (ABI) and Cardiac Ankle Vascular Index (CAVI) and Prognosis in Maintenance Hemodialysis Patients

Session Information

Category: Hypertension and CVD

  • 1401 Hypertension and CVD: Epidemiology, Risk Factors, and Prevention

Authors

  • Yasuda, Kaoru, Masuko Memorial Hospital, Department of Nephrology, Nagoya, Japan
  • Maruyama, Shoichi, Nagoya University Graduate School of Medicine, Nagoya, Japan
  • Morozumi, Kunio, Masuko Memorial Hospital, Nagoya, AICHI-KEN, Japan
Background

Ankle brachial blood index (ABI) and cardiac ankle vascular index (CAVI) are both indicators of systemic atherosclerosis. We investigate the relationship between ABI and CAVI in maintenance hemodialysis patients and their prognosis.

Methods

We measured ABI and CAVI for 297 patients undergoing maintenance hemodialysis treatment at Masuko memorial hospital. The cut-off value of CAVI was calculated by ROC analysis.

Results

During the observation period (median 28 months), 47 cases (15.8%) died. In 2-year survival rate, the ABI abnormal group (<0.9, n = 92) was significantly lower than in the normal group (> 0.9, n = 205) (67.7% vs. 92.6%, p <0.0001, adjusted hazard ratio 2.18). There was no difference in the survival rate between the CAVI abnormal group (> 9.0, n = 91) and the normal group (<9.0, n = 114) in the ABI normal group (91.1% vs. 93.6%, p = 0.74). However, when a new cut-off value (7.9) by ROC analysis was used, 2-year survival rate in the CAVI abnormality group (n = 137) was significantly lower than that in the normal group (n = 68) (88.7% vs. 98.5%, p = 0.021).

Conclusion

CAVI as a prognostic indicator should have a lower Cut-off value in maintenance hemodialysis patients with increased arteriosclerosis than the Cut-off value used by general population. In addition, it was suggested that even with normal ABI patients, it is possible to stratify prognostic risk by measuring CAVI.