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Abstract: FR-PO672

Low-Volume Tidal Peritoneal Dialysis Is a Preferable Mode in Patients Initiating Urgent-Start Automated Peritoneal Dialysis

Session Information

Category: Dialysis

  • 703 Dialysis: Peritoneal Dialysis

Authors

  • Xie, Jianteng, Guangdong General Hospital, Guangdong Academy of Medical Sciences, GuangZhou, GUANGDONG, China
  • Wang, Huizhen, Guangdong General Hospital, Guangdong Academy of Medical Sciences, GuangZhou, GUANGDONG, China
  • Li, Jing, Guangdong General Hospital, Guangdong Academy of Medical Sciences, GuangZhou, GUANGDONG, China
  • Liang, Tiantian, Guangdong General Hospital, Guangdong Academy of Medical Sciences, GuangZhou, GUANGDONG, China
  • Wang, Yanhui, Guangdong General Hospital, Guangdong Academy of Medical Sciences, GuangZhou, GUANGDONG, China
  • Zhang, Yifan, Guangdong General Hospital, Guangdong Academy of Medical Sciences, GuangZhou, GUANGDONG, China
  • Wang, Wenjian, Guangdong General Hospital, Guangdong Academy of Medical Sciences, GuangZhou, GUANGDONG, China
Background

To evaluate the safety of low-volume tidal peritoneal dialysis (TPD) and intermittent peritoneal dialysis (IPD) in end-stage renal disease (ESRD) patients initiating automated peritoneal dialysis (APD) after an acute catheter insertion.

Methods

Clinical outcomes of patients who received either TPD or IPD using an APD system were compared in a randomized, open-label, prospective control study in a single-center setting.
From May 2011 to May 2013, 49 patients were enrolled and 27 patients received low-volume TPD treatment whereas 22 patients underwent low-volume IPD right after Tenckhoff catheter insertion. The incidence of complications during the 14-day APD treatment were observed. After APD treatment, all the patients were transferred to continuous ambulatory peritoneal dialysis (CAPD) and followed up for 2 years.

Results

The IPD group demonstrated a significantly high incidence of catheter-related complications than the TPD group after adjusting for age, gender, baseline diabetes, systolic blood pressure, and body mass index. However, the short duration of APD treatment with either IPD or TPD mode did not affect the long-time technical survival.

Conclusion

In patients immediately after catheter insertion, low-volume TPD mode demonstrated a lower incidence of catheter-related complications compared to IPD. However, definitive conclusions about TPD benefit cannot be made, owing to early termination of the trial.

Patient characteristics at baseline.

The incidence of complications during 2-week APD treatment.