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Abstract: TH-PO1070

CKD and At-Risk of CKD Registry: CURE-CKD

Session Information

Category: CKD (Non-Dialysis)

  • 1901 CKD (Non-Dialysis): Epidemiology, Risk Factors, and Prevention

Author

  • Alicic, Radica Z., Providence Medical Research Center, Spokane, Washington, United States
Background

Most healthcare systems have not been proactively prepared to identify patients with or at-risk of chronic kidney disesase (CKD) to improve care and clinical outcomes. The aim of this study was to classify and describe these patients in two large healthcare systems.

Methods

PSJH and UCLA healthcare systems collaboratively formed a registry (CURE-CKD) from their respective electronic health records (EHR). Participants were identified by a diagnosis of CKD or at-risk of CKD (diabetes, hypertension, pre-diabetes) by ICD-9/10 codes, guideline-based clinical criteria, and medication specific to a particular condition from the years 2006-2016.

Results

CURE-CKD includes 2,401,403 individuals. The table shows baseline characteristics by CKD (N=554,051) and at-risk of CKD (N=1,847,352) groups.

Conclusion

Real world, practice-based evidence can be used to classify patients as a platform for strategies to prevent CKD progression and complications as well as incident CKD.

DemographicsCKD (N=554,051)At-Risk (N=1,847,352)
Gendern%n%
Men241,93844898,99149
Women312,08156947,81051
Race    
White404,713731,252,77968
Black26,685586,4215
Asian28,5815103,1866
Not Classified85,81116376,12720
Dwelling location    
Rural66,41012210,41111
Urban482,829871,621,07788
Conditionsn%n%
Diabetes*249,25945597,03032
Hypertension*388,121701,370,55174
Pre-diabetes*87,17416315,09517
Clinical CharacteristicsmeanSDmeanSD
Age (years)71185717
eGFR (mL/min/1.73m2)61269021
Systolic blood pressure
(mm Hg)
1301813016
HbA1c (%; diabetes subset)7272
CKD stagen%n%
CKD 1-2247,38545--
CKD 3233,90342--
CKD 432,8456--
CKD 519,6114--
CKD unstaged**20,3074--

*diabetes, hypertension and/or pre-diabetes are not mutually exclusive conditions, **identified by ICD code without CKD stage

Funding

  • Private Foundation Support