Abstract: TH-PO1070
CKD and At-Risk of CKD Registry: CURE-CKD
Session Information
- CKD: Epidemiology, Risk Factors, Prevention - I
October 25, 2018 | Location: Exhibit Hall, San Diego Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: CKD (Non-Dialysis)
- 1901 CKD (Non-Dialysis): Epidemiology, Risk Factors, and Prevention
Author
- Alicic, Radica Z., Providence Medical Research Center, Spokane, Washington, United States
Background
Most healthcare systems have not been proactively prepared to identify patients with or at-risk of chronic kidney disesase (CKD) to improve care and clinical outcomes. The aim of this study was to classify and describe these patients in two large healthcare systems.
Methods
PSJH and UCLA healthcare systems collaboratively formed a registry (CURE-CKD) from their respective electronic health records (EHR). Participants were identified by a diagnosis of CKD or at-risk of CKD (diabetes, hypertension, pre-diabetes) by ICD-9/10 codes, guideline-based clinical criteria, and medication specific to a particular condition from the years 2006-2016.
Results
CURE-CKD includes 2,401,403 individuals. The table shows baseline characteristics by CKD (N=554,051) and at-risk of CKD (N=1,847,352) groups.
Conclusion
Real world, practice-based evidence can be used to classify patients as a platform for strategies to prevent CKD progression and complications as well as incident CKD.
| Demographics | CKD (N=554,051) | At-Risk (N=1,847,352) | ||
| Gender | n | % | n | % |
| Men | 241,938 | 44 | 898,991 | 49 |
| Women | 312,081 | 56 | 947,810 | 51 |
| Race | ||||
| White | 404,713 | 73 | 1,252,779 | 68 |
| Black | 26,685 | 5 | 86,421 | 5 |
| Asian | 28,581 | 5 | 103,186 | 6 |
| Not Classified | 85,811 | 16 | 376,127 | 20 |
| Dwelling location | ||||
| Rural | 66,410 | 12 | 210,411 | 11 |
| Urban | 482,829 | 87 | 1,621,077 | 88 |
| Conditions | n | % | n | % |
| Diabetes* | 249,259 | 45 | 597,030 | 32 |
| Hypertension* | 388,121 | 70 | 1,370,551 | 74 |
| Pre-diabetes* | 87,174 | 16 | 315,095 | 17 |
| Clinical Characteristics | mean | SD | mean | SD |
| Age (years) | 71 | 18 | 57 | 17 |
| eGFR (mL/min/1.73m2) | 61 | 26 | 90 | 21 |
| Systolic blood pressure (mm Hg) | 130 | 18 | 130 | 16 |
| HbA1c (%; diabetes subset) | 7 | 2 | 7 | 2 |
| CKD stage | n | % | n | % |
| CKD 1-2 | 247,385 | 45 | - | - |
| CKD 3 | 233,903 | 42 | - | - |
| CKD 4 | 32,845 | 6 | - | - |
| CKD 5 | 19,611 | 4 | - | - |
| CKD unstaged** | 20,307 | 4 | - | - |
*diabetes, hypertension and/or pre-diabetes are not mutually exclusive conditions, **identified by ICD code without CKD stage
Funding
- Private Foundation Support