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Abstract: FR-PO843

Weight Gain in the First Year Post Kidney Transplantation

Session Information

Category: Transplantation

  • 2002 Transplantation: Clinical

Authors

  • Arabi, Ziad, Division of Nephrology, King Abdulaziz Medical City, Riyadh, Saudi Arabia
  • Aljabri, Jawaher Nayyaf, Division of Nephrology, King Abdulaziz Medical City, Riyadh, Saudi Arabia
  • Tawhari, Mohammed Hadi, Division of Nephrology, King Abdulaziz Medical City, Riyadh, Saudi Arabia
Background

Undesirable weight gain following kidney transplantation (KT) is relatively common. In this study we examined the incidence and risk factors for weight gain of >5% in the first post-transplantation year.

Methods

A single center retrospective study of the kidney transplant recipients (KTR) who underwent KT between 2017 to 2020 with 12 months follow up. We reviewed the patients’ demographics, weight changes and A1C values. We also examined the factors associated with weight gain >5%.

Results

A total of 287 KTR were included. 74% were ≥ 30 years, 58% were men and 80% were living-donor KTR. Preemptive KT was 10.1%, PD: 11.5% and HD: 78.4%. At baseline, 20.2% of patients had obesity stage 1 (BMI: 30-34.9), while 4.2% had obesity stage 2 (BMI 35-39.9). Diabetes (DM) was present in 34.5% (n=99) of whom 25.3% had type-1 DM while 74.7% had type-2 DM.

The average weight gain by one year of transplant was 6.0±8.3 (kg) and 59.6% patients had weight increase of ≥5%.
Both males and females significantly gained weight and in a comparable degree (p: 0.588). Weight gain after living donor KT was much more than after deceased donor KT [6.63 Kg (5.58 to 7.69) versus 3.42 Kg (1.12 to 5.71). p: 0.009].
Multivariate analysis showed that the odd ratio of weight gain ≥ 5% after living donor KT (versus deceased donor) is OR: 2.86 (CI: 1.49 to 5.523, p: 0.002).
Baseline BMI was negatively associated with weight gain post KT (OR:0.9, CI: 0.854 to 0.949, p: <0.00). Age, gender, DM and hypertension were not associated with higher weight gain.

Conclusion

About two thirds of the renal transplant recipients gain at least ≥5% of their baseline weight by the first year after kidney transplantation. Recipients of living donor kidney transplant and those with lower BMI are at increased risk factor.