Abstract: SA-PO143
Treatment Patterns for Low-Risk Prostate Cancer in Dialysis, Kidney Transplant, and Non-Dialysis
Session Information
- Onconephrology: Clinical and Research Advances - II
November 05, 2022 | Location: Exhibit Hall, Orange County Convention Center‚ West Building
Abstract Time: 10:00 AM - 12:00 PM
Category: Onconephrology
- 1600 Onconephrology
Authors
- Sarabu, Nagaraju, University Hospitals, Cleveland, Ohio, United States
- Dong, Weichuan, Case Western Reserve University, Cleveland, Ohio, United States
- Koroukian, Siran M., Case Western Reserve University, Cleveland, Ohio, United States
Background
Patients with end stage kidney disease being evaluated for transplant are screened for prostate cancer. When a cancer is found, it is often treated given concerns about transplant eligibility in the presence of a malignancy.
Methods
Retrospective population based observational cohort study, using Surveillance, Epidemiology, and End Results-Medicare data (Males > 40 years with localized prostate cancer (2010 – 2015). Compared low risk localized prostate cancer treatment patterns and mortality rates among dialysis, kidney transplant and non-dialysis patients using logistic regression and cox proportional hazards models.
Results
A total of 46 low risk prostate cancer dialysis patients and 20 kidney transplant patients were identified. We age-matched 42 dialysis patients to 210 non-dialysis patients (Table 1). Non-dialysis patients with low-risk prostate cancer were less likely, OR: 0.080.270.8 to get curative treatment, and high mortality, as compared to dialysis patients. None of the kidney transplant patients in low-risk group died of prostate cancer.
Conclusion
Dialysis patients, who are more likely to die of other causes, are paradoxically more likely to be treated for low-risk prostate cancer. Active surveillance should be performed in this population, and should not preclude transplant eligibility.
Baseline Characteristics. Numbers < 11 are masked according to SEER-Medicare policy.