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Abstract: TH-PO885

Predictors of CKD Awareness in Middle-Aged and Older Community-Dwelling Japanese Adults

Session Information

Category: CKD (Non-Dialysis)

  • 2201 CKD (Non-Dialysis): Epidemiology‚ Risk Factors‚ and Prevention

Authors

  • Kabasawa, Keiko, Niigata University, Niigata, Japan
  • Ito, Yumi, Niigata University, Niigata, Japan
  • Nakamura, Kazutoshi, Niigata University, Niigata, Japan
  • Tanaka, Junta, Niigata University, Niigata, Japan
  • Narita, Ichiei, Niigata University, Niigata, Japan
Background

Despite global efforts in public health campaigns on chronic kidney disease (CKD), CKD awareness, which is a key to improving health outcomes through patient engagement, remains low. Predictors of CKD awareness may help identify effective ways to raise awareness but are not yet clear. In this study, we aimed to determine clinical and socio-demographic characteristics associated with CKD awareness.

Methods

Using the 5-year longitudinal framework of the Uonuma cohort study, we analyzed data of 5,932 Japanese adults (median age at baseline, 61 years; range, 40-92 years; 50.7% women) who participated in the baseline (2012-2014) and 5-year surveys and in a health checkup at the study’s 5-year follow-up. CKD awareness was defined as answering the question “Have you ever been told by a doctor that you have chronic kidney disease (abnormal urinalysis or kidney dysfunction)?” with “Yes, I was told within the past 5 years.” A self-administered questionnaire collected clinical history, socio-demographic characteristics, and family history of CKD. At the 5-year health checkup, CKD was diagnosed based on eGFR <60 mL/min/1.73 m2 or ≥1+ dipstick urine protein.

Results

At the 5-year follow-up, there were 1,232 participants (20.8%) who had CKD, with mean eGFR of 73.6 (standard deviation 15.0) mL/min/1.73 m2. The sensitivity and specificity of the CKD awareness question were respectively 15.4% and 97.7% in men and 9.3% and 99.1% in women. In demographic-adjusted logistic regression analysis, family history of CKD and history of heart disease, stroke, hypertension, diabetes, and hyperuricemia were significantly associated with CKD awareness, but these associations were not significant in multivariable logistic regression analysis with further adjustment for eGFR. In the multivariable logistic regression model, independent predictors of CKD awareness were history of urinary tract stone (adjusted odds ratio [95% confidence interval], 2.08 [1.33-3.25]), female sex (0.47 [0.35-0.64]), and married status (0.62 [0.45-0.87]).

Conclusion

The results of this study suggest that known risk factors for CKD did not predict CKD awareness independently of kidney function and that a sex-dependent approach may help to improve CKD awareness.

Funding

  • Government Support – Non-U.S.