Abstract: SA-PO807
Outcomes of Commercial Renal Transplantation: A Single Center Experience
Session Information
- Transplantation: Clinical - Pretransplant Assessment and Living Donors
November 05, 2022 | Location: Exhibit Hall, Orange County Convention Center‚ West Building
Abstract Time: 10:00 AM - 12:00 PM
Category: Transplantation
- 2002 Transplantation: Clinical
Author
- El Agroudy, Amgad E., Arabian Gulf University, Manama, Bahrain
Background
While the ethical aspects of transplant tourism have received much attention recently, less has been written about the medical safety of this practice. We retrospectively evaluated the outcomes of patients who purchased organs internationally and presented to our center for follow-up care.
Methods
We report the outcome parameters of 270 local recipients of unrelated kidney (URT) vendor transplants presenting to our institute between 1986 and 2014. Their outcome was compared with 123 recipients of living-related donor transplants matched for age, gender and transplant duration done in our center as controls (RT).
Results
Age of unrelated recipients was 42.6 ± 13.4 years with Male % of 68. The country of transplant was mainly in Philippines (n = 85), Pakistan (n = 56), India (n = 57), Iran (n = 40) and Egypt (n= 25). Comparison of commercial recipients with controls showed high co morbidities (P = 0.01) with hepatitis-C (n=2 vs. 0) and hepatitis-B (n=2 vs. 0) and cytomegalovirus (n=4 vs. 1). Donor age was 25.9 ± 3.8 vs. 34.6 ± 8.6 years (P = 0.0001) and 90.4% were male. Biologic agents induction in 74 (27.4%) vs. 123 (100%) (P = 0.00001), acute rejections in 65 (24.1%) vs. 26 (21.1%) (P = 0.7), while recurrent rejection in 13 (4.8%) vs. 1 (0.8%) (P = 0.04), surgical complications including lymphocele 16 (5.9%) vs. 0 (0%) (P = 0.0001), ureteral obstruction 7 (2.6%) vs. 0 (0%) (P = 0.007), hematoma 4 (1.5%) vs. 1 (1.1%) (P = 0.06) and recurrent urinary tract infection 18 (9.9%) vs. 6 (6.8%) (P = 0.3). Overall 1- and 10-year for graft survival was 91% and 22% vs. 98% and 44% and for patient survival 96% and 70% vs. 98% and 78% in URT and RT, respectively (P = 0.001)
Conclusion
Although recent developments increased success in renal transplantation, receiving a kidney from a paid living donor at a commercial transplant center still carries great risks for the recipient.