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Abstract: SA-PO180

Seasonality in Hip Fracture Among Hemodialysis Patients and Kidney Transplant Recipients in South Korea

Session Information

Category: Bone and Mineral Metabolism

  • 402 Bone and Mineral Metabolism: Clinical

Authors

  • Song, Young Woo, Catholic University of Korea Incheon Saint Mary's Hospital, Incheon, Incheon, Korea (the Republic of)
  • Park, Jin Ah, Catholic University of Korea Incheon Saint Mary's Hospital, Incheon, Incheon, Korea (the Republic of)
  • Shin, Seok Joon, Catholic University of Korea Incheon Saint Mary's Hospital, Incheon, Incheon, Korea (the Republic of)
  • Lee, Joo Eun, Catholic University of Korea Incheon Saint Mary's Hospital, Incheon, Incheon, Korea (the Republic of)
  • Eum, Sang Hun, Catholic University of Korea Incheon Saint Mary's Hospital, Incheon, Incheon, Korea (the Republic of)
  • Yoon, Hye Eun, Catholic University of Korea Incheon Saint Mary's Hospital, Incheon, Incheon, Korea (the Republic of)
  • Lee, Yeonhee, Catholic University of Korea Incheon Saint Mary's Hospital, Incheon, Incheon, Korea (the Republic of)
Background

The seasonality of hip fracture in hemodialysis (HD) patients and kidney transplant recipients (KTRs) have not been reported. We assessed seasonal variations in hip fractures among patients with end-stage kidney disease who undergo maintenance HD and KTRs.

Methods

Using the Korean National Health Insurance System database from January 2012 to December 2017, monthly counts of hip fracture were calculated among HD patients (n = 77,420) and KTRs (n = 8,921)(Fig 1.). The 6-year normalized monthly fraction and seasonal fractions of hip fractures were calculated. A cosinor analysis was performed to determine the seasonality of the monthly incidence of hip fractures.

Results

The 6-year average monthly fraction of hip fractures was lowest in June and highest in October in HD patients, and lowest in February and highest in November in KTRs. The 6-year average seasonal fraction among HD patients was lowest in summer and highest in winter, and lowest in summer and highest in autumn among KTRs, both without statistical significance. The incidence ratio of hip fractures was lowest in June and highest in January in HD patients, and lowest in August and highest in November in KTRs. On cosinor analysis, HD patients showed significant seasonality in hip fracture incidence, with a trough in summer and a peak in winter (P = 0.002), whereas KTRs did not exhibit a significant trend (P = 0.293)(Fig 2.).

Conclusion

Hip fractures occurred more frequently in winter and less frequently in summer in patients undergoing HD, whereas KTRs did not show a seasonal trend.