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Abstract: FR-PO929

Full Age Spectrum eGFR Formula Corrected by Height to Adapt to a Population Endemic to Mesoamerican Nephropathy as a Tool to Diagnose and Follow Up CKD

Session Information

Category: CKD (Non-Dialysis)

  • 2201 CKD (Non-Dialysis): Epidemiology‚ Risk Factors‚ and Prevention


  • Sidoti, Antonino, Nefrologia Valdelsa, Poggibonsi, Siena, Italy
  • Sequeira, María Jose, Fundacion Coen, Chinandega, Chinandega, Nicaragua
  • Mazzacani, Paolo, Fundacion Coen, Chinandega, Chinandega, Nicaragua

Group or Team Name

  • Clinica Nefrologia Fundacion Coen Chinandega

We have to diagnose monitor for developing CKD and follow up people age 12-20 affected and by Mesoamerican Nephropathy. Recommendation is from NKDEP to notate values from Schwartz formula (Schw) above 75 ml/min' as 75 ml/min' due to inaccuracy. CKD-EPI is not suitable to a pediatric cohort, we have to follow children after their passage to adult age. Our attention is focused on Full Age Spectrum formula (FAS) (Pottel: 2017, 2020) that is recommended to be adapted whenever used to the population at hand.


We completed 1099 records with creatinine, height, weight, age. FAS was winsored at 169.5 ml/min' using Q-Q graph, as a consequence Schw was winsored at 169.5. Adjustment of FAS for height (FASAdj) was accomplished using a people categorization via Schw values for eGFR < 60 n=11, < 75 n=153 and above 75 ml/min' n= 935 and applying FAS Pearson coefficients via a sub-categorization by sex also. Bland- Altman analysis was performed using Schw as standard method.


Fig 1 and Fig 2 show Bland-Altman analysis for eGFR < 60 and < 75 ml/min'. On the whole cohort mean difference between Schw and FASAdj was -11.98, 1.96 SD lies between +9.42 and -33.39.


FASAdj seems suitable as a tool for diagnosis and follow up of CKD, is adapted to the population to monitor; differences from Schw seem not clinically significant particularly in the eGFR level below 75 ml/min'.


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