Abstract: FR-PO0102
Predictive Value of Nutritional Scores, Including Controlling Nutritional Status (CONUT), Geriatric Nutritional Risk Index (GNRI), and Prognostic Nutritional Index (PNI), for Contrast-Induced AKI (CI-AKI) in Patients with Diabetes Undergoing Coronary Angiography (CAG)/Percutaneous Coronary Intervention (PCI)
Session Information
- AKI: Epidemiology and Clinical Trials
November 07, 2025 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Acute Kidney Injury
- 102 AKI: Clinical, Outcomes, and Trials
Authors
- Du, Xia, Sir Run Run Hospital Nanjing Medical University, Nanjing, Jiangsu, China
- Ma, Mengqing, Nanjing First Hospital, Nanjing, Jiangsu, China
- Cao, Changchun, Sir Run Run Hospital Nanjing Medical University, Nanjing, Jiangsu, China
Background
This study included 2,043 type 2 diabetes patients(2022-2023). CI-AKI was defined by serum creatinine criteria. Multivariable analyses identified risk factors, with ROC/AUC evaluating predictive performance. RCS and a nomogram quantified nonlinear relationships and individualized risk.
Methods
This retrospective cohort included 2,043 type 2 diabetes patients from two tertiary centers (2021-2023). CI-AKI was defined by serum creatinine criteria. Multivariable analyses identified risk factors, with ROC/AUC evaluating predictive performance. Restricted cubic splines (RCS) and a nomogram quantified nonlinear relationships and individualized risk.
Results
CI-AKI occurred in 273 patients (13.4%). Independent predictors included GNRI (OR=0.912) and PNI (OR=0.812). PNI had superior discrimination (AUC=0.871, P<0.001) vs. GNRI (AUC=0.755, P<0.001)) and CONUT (AUC=0.547). The nomogram achieved 80% accuracy.
Conclusion
GNRI and PNI predict CI-AKI and adverse outcomes in diabetic patients undergoing CAG/PCI better than CONUT.
Table 1. Multivariate logistic regression analysis of CI-AKI occurrence.
| Variables | OR | 95% Cl | P value |
| Female | 1.816 | 1.160-2.440 | 0.009 |
| Preoperative systolic blood pressure | 1.018 | 1.008-1.028 | <0.001 |
| Neutrophil count | 1.060 | 1.021-1.101 | 0.002 |
| Preoperative glucose | 1.093 | 1.041-1.147 | <0.001 |
| Hematuria positive | 1.785 | 1.260-2.528 | 0.001 |
| Diuretics | 3.643 | 2.595-5.116 | <0.001 |
| CONUT | 1.055 | 0.971-1.145 | 0.207 |
| GNRI | 0.912 | 0.889-0.936 | <0.001 |
| PNI | 0.812 | 0.776-0.850 | <0.001 |
Figure 1. ROC curves of three nutritional scores for predicting CI-AKI.
Figure 2. Nomogram for Predicting the Incidence of CI-AKI.
Funding
- Government Support – Non-U.S.