Abstract: TH-PO1041
CKD Awareness and Risk Factor Control in US Adults: Findings from NHANES, 2009-2020
Session Information
- CKD: Epidemiology, Risk Factors, and Other Conditions
November 06, 2025 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: CKD (Non-Dialysis)
- 2301 CKD (Non-Dialysis): Epidemiology, Risk Factors, and Prevention
Authors
- Chow, Timothy Michael, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States
- Ishigami, Junichi, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States
Background
Chronic kidney disease (CKD) is a major global health concern. Contemporary management focuses on risk factor control to limit progression to kidney failure. Yet, nearly 90% of individuals with CKD in the US are unaware of their diagnosis—missing opportunities for intervention. This study examines risk factor control and clinical management in individuals with CKD, comparing those aware vs. unaware using National Health and Nutrition Examination Survey (NHANES) data.
Methods
Baseline characteristics were compared by CKD awareness. The proportion aware was evaluated overall, across CKD stages, and across NHANES cycles. Univariate and multivariable logistic regression analyses estimated the odds of achieving each risk factor control or medication use, comparing those aware vs. unaware.
Results
In pooled NHANES samples, only 10.1% were aware of CKD. Awareness increased with worsening eGFR and albuminuria. Among those with CKD G4/G5, only 51% were aware.
In crude models, factors positively associated with CKD awareness included statin use (OR = 2.07, 95% CI 1.68–2.56), RASi use (OR = 1.94, 95% CI 1.51–2.48), and LDL-C control <160 mg/dL (OR = 1.95, 95% CI 1.06–3.59). When modeling interactions with hypertension, diabetes, and CHD, CKD awareness was significantly associated with RAAS inhibitor use (OR = 3.63, 95% CI 1.23–10.70) and HbA1c control <8.0% (OR = 5.93, 95% CI 1.11–31.72).
Conclusion
Despite increased awareness with increased CKD severity, awareness of CKD remains remarkably low. Those aware of CKD are likely to be aware of other conditions. Risk factor control were similar in those aware and not aware of their CKD with the exception of use of RAAS blockade which was more likely in those aware of CKD.
Funding
- Other NIH Support