Kidney Week

Abstract: FR-PO0110

Implementation and Outcomes of a Continuous Quality Improvement Program in Continuous Renal Replacement Therapy at Tertiary Care Hospitals

Session Information

• AKI: Epidemiology and Clinical Trials
  November 07, 2025 | Location: Exhibit Hall, Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: Acute Kidney Injury

• 102 AKI: Clinical, Outcomes, and Trials

Authors

• Mercado Hernández, Yazmin Alejandra, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, CDMX, Mexico

Yazmin Alejandra Mercado Hernández, MD

• Vega, Olynka, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, CDMX, Mexico

Olynka Vega, MD

• Galindo, Pablo E., Hospital General de Mexico Dr Eduardo Liceaga, Mexico City, CDMX, Mexico

Pablo E. Galindo, MD

• Mendez Morales, Mario Alejandro, Hospital General de Mexico Dr Eduardo Liceaga, Mexico City, CDMX, Mexico

Mario Alejandro Mendez Morales, PhD

Background

The aim of this study was to compare the degree of goal achievement in quality metrics (QMs) for continuous renal replacement therapy (CRRT) before and after the sequential implementation of a continuous quality improvement program (CQIP) in two university hospitals.

Methods

This ambispective study was divided into three periods: Period 1 (retrospective, 2016–2019), before CQIP implementation in hospital 1; Period 2 (prospective, 2020–2023), after CQIP implementation in hospital 1; Period 3 (prospective, 2024–2025), after initiating a CRRT program in hospital 2 with the CQIP. The CQIP included regional citrate anticoagulation (RCA) and continuing education for staff. Clinical and technical data were collected, QMs calculated, and comparisons made across the periods.

Results

A total of 209, 412, and 377 CRRT sessions were performed in 59, 93, and 89 patients during periods 1, 2, and 3, respectively. RCA was used in 46.5% of sessions in period 2 and 77% in period 3. The median filter lifespan increased from 36.5 h in period 1 to 64 h in period 2, and 81 h in period 3. The proportion of filters lasting >60 h rose from 23% to 54.5%, and 71%, respectively. Sessions with a delivered/prescribed dose ratio >80% increased from 84% to 94%, and those with downtime <10% rose from 65.5% to 74%. Overall, goal achievement improved significantly in period 3 compared to the previous periods.

Conclusion

These improvements in filter performance and QMs reflect the positive impact of CQIP implementation on CRRT delivery and patient care.

Digital Object Identifier (DOI)

• doi: 10.1681/ASN.2025xestmrjg