Abstract: FR-PO1050
Effect of Dialysis Adequacy on Quality of Life in Patients on Maintenance Hemodialysis
Session Information
- Hemodialysis: Clinical Challenges, Patient-Centered Outcomes, and Quality of Life
October 23, 2026 | Location: Exhibit Hall A, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 801 Dialysis: Hemodialysis and Frequent Dialysis
Authors
- Kumar, Sandeep, Max Super Speciality Hospital Vaishali, Ghaziabad, UP, India
- Grover, Sugandha, Max Super Speciality Hospital Vaishali, Ghaziabad, UP, India
Background
Patients on maintenance hemodialysis have significant impairments in health-related quality of life and nutrition.This study assessed the outcomes of adequacy of dialysis in terms of solute clearance (Kt/V) with quality of life and nutritional status of patient on maintenance hemodialysis. Many studies have investigated the link between hemodialysis adequacy and quality of life, but most have relied on spKt/V as the primary measure. While spKt/V is a commonly used parameter, it may not be the most accurate indicator when comparing patients on different dialysis schedules.
Methods
We performed an observational, cross-sectional study.All the patients above 18 years on maintenance hemodialysis for more than 3 months at our centre were included in the study.Hemodialysis adequacy was assessed using weekly standard Kt/V. Quality of life was assessed by KDQOL short form SF 36 (KDQOL-SF-36) health survey.Nutritional status was assessed using Modified Subjective Global Assessment (SGA) dialysis malnutrition score .
Results
Of 203 patients, 80 had achieved std Kt/V ≥ 2.1 and 123 patients had std Kt/V <2.1.Quality of life as indicated by total SF 36 score was similar in both groups (58.17±0.07 vs 56.19±11.28 , p = 0.205)Quality of life score was not different in patient receiving twice a week as compared to thrice a week hemodialysis (50.02±15.03 vs 48.73±12.12 respectively, p=0.499).Sixty patients (75 %) in the group with std Kt/V ≥ 2.1 were malnourished (mild 42 (52.5%); moderate 18 (22.5%)) as compared to ninety one (74 %) patient in std Kt/V < 2.1 (mild 53 (43.4%) ; moderate 38 (31.1%)).Moderate malnutrition was more common in the group with std Kt/V <2.1 (31.1.% vs 22.5%, p=0.341) and in patients receiving twice a week dialysis (35.8% vs 20.6%, p =0.046)
Conclusion
This cross-sectional study demonstrates that small solute clearance or frequency of dialysis did not influence the quality of life as assessed by SF-36.Nutritional status was better in patients who were on thrice a week dialysis and in patient who could achieve std Kt/V≥ 2.1.