Abstract: FR-PO1069
Clinical Profile and Outcomes of Patients on Peritoneal Dialysis Presenting with Fluid Overload at the Emergency Department: A Single-Center Prospective Study
Session Information
- Home Dialysis: Modalities, Barriers, Utilization, and Clinical Outcomes
October 23, 2026 | Location: Exhibit Hall A, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 802 Dialysis: Home Dialysis and Peritoneal Dialysis
Authors
- Sobremisana, James Areja, National Kidney and Transplant Institute, Quezon City, NCR, Philippines
- Estabillo, Amor Patrice Socorro Espinosa, National Kidney and Transplant Institute, Quezon City, NCR, Philippines
- Imperial, Pamela Marie Blanco, National Kidney and Transplant Institute, Quezon City, NCR, Philippines
Background
Fluid overload is a common and potentially preventable complication among patients with end-stage renal disease (ESRD) undergoing peritoneal dialysis (PD). It contributes significantly to cardiovascular morbidity, hospital readmissions, and healthcare costs. This study aimed to describe the clinical profiles, management strategies, outcomes, and costs of PD patients with fluid overload presenting to the Emergency Department (ED) of the National Kidney and Transplant Institute (NKTI), as data on this population are still lacking in the Philippines.
Methods
This descriptive prospective study examined adult patients on continuous ambulatory peritoneal dialysis (CAPD) with signs and symptoms of fluid overload who fulfilled the inclusion and exclusion criteria at NKTI ED from June 2025 to November 2025, analyzing their demographics, clinical findings, management, costs, and outcomes. The primary outcome was in-hospital mortality, while secondary outcomes included the need for Intensive Care Unit (ICU) admission, invasive ventilation, discharged improved, length of hospital stay, 90-day readmission, transfer to hemodialysis, and continued use of CAPD.
Results
Out of 412 PD-related ED visits, 21 (5.1%; 95% CI: 2.97–7.22%) were for fluid overload. The mean age was 43.6 ± 11.1 years, with a predominantly male population (61.9%), and most are unemployed (90.5%). Upon presentation, 80.9% had peripheral edema, 76.2% were hypertensive, and weight gain was +1.5 kg (IQR −1.35 to +4.75) from baseline. Their laboratory results revealed elevated creatinine (13.11 ± 4.34 mg/dL), hyponatremic (mean 133 mmol/L), and hypoalbuminemic (mean 3.05 g/dL). Most patients received automated PD and prescription revisions at the ED. All patients were discharged improved after a median stay of 3 days; 1 (4.8%) patient required invasive ventilation, and 3 (14.3%) were shifted to hemodialysis. Readmission within three months was 42.9%, and the median hospitalization cost was 64,660 Philippine Peso (around 1,080 USD).
Conclusion
Fluid overload in peritoneal dialysis patients presents a significant clinical and economic challenge. While short-term outcomes were positive, high readmission rates highlight the need for better outpatient monitoring and care strategies. Focusing on patient education, clinical monitoring of signs of overload can improve long-term outcomes.
Acknowledgment
The authors sincerely thank the ethics and research board for the guidance and support throughout this research. The Grammarly tool was used during manuscript preparation to assist with grammar and language clarity. The authors reviewed all revisions and suggestions and remain fully responsible for the ideas, accuracy, interpretation, and integrity presented in this work.