Abstract: PUB088
Prevalence of Hyperkalemia and Its Epidemiological Associations at a Tertiary Care Hospital in Guadalajara, Jalisco, Mexico
Session Information
Category: Fluid, Electrolytes, and Acid-Base Disorders
- 1102 Fluid, Electrolyte, and Acid-Base Disorders: Clinical
Authors
- Marmolejo Bedolla, Hector Manuel, Hospital San Javier, Guadalajara, Jal., Mexico
- Chirinos Gómez, Omar, Hospital San Javier, Guadalajara, Jal., Mexico
- Lamadrid Gámez, Karina, Hospital San Javier, Guadalajara, Jal., Mexico
- Díaz Sánchez, Verónica Monserrat, Hospital San Javier, Guadalajara, Jal., Mexico
- Macías, Lucio Octavio Sánchez, Hospital San Javier, Guadalajara, Jal., Mexico
Background
Hyperkalemia is a common condition among hospitalized patients, particularly those with chronic kidney disease, diabetes, and heart failure, and is associated with increased morbidity and mortality. With a reported global incidence of 1–10%, this condition can lead to fatal outcomes such as cardiac arrhythmias or skeletal muscle weakness, underscoring the need for protocols for its detection and management.
Methods
A retrospective descriptive study of patients hospitalized with hyperkalemia at San Javier Hospital between May 2023 and February 2024. Clinical and epidemiological variables were analyzed; tests included the Kolmogorov-Smirnov, chi-square, Fisher’s exact, Mann-Whitney U, Kruskal-Wallis, and Wilcoxon tests. Analyses were performed using SPSS v24.0, GraphPad Prism v7.0, and Excel, with a p-value < 0.05 considered statistically significant.
Results
The study included 201 patients (48.3% women, 51.7% men), with a mean age of 65.9 years. Chronic kidney disease was the most common comorbidity. The most common treatments were watchful waiting (30%) and multiple combinations (27%). Following treatment, an overall decrease in serum potassium was observed, with no differences in mortality based on comorbidities or type of management.
Conclusion
The results of this study showed that hyperkalemia has a heterogeneous epidemiological profile, with significant differences by sex and age, noting that affected women had a higher average age. Furthermore, diabetes mellitus, heart failure, hypertension, and stage of chronic kidney disease were not independently associated with elevated potassium levels. No significant differences in mortality were observed based on initial treatment, although there was an overall reduction in potassium levels following intervention. Mortality did not differ in patients with diabetes mellitus, and although it was higher in those with heart failure, this association did not reach statistical significance.
Acknowledgment
Special thanks to Dr Lucio because he was guiding us all over this years. Thanks to Dr Karina for including me at this proyect and give us the information of her investigation, to Monse & Omar because they were helping to analize, syntetize and present the cartel.
Funding
- Private Foundation Support