Abstract: FR-PO1006
When Your Eyes Can't Keep Up: A Case of Ocular Disequilibrium Syndrome
Session Information
- Hemodialysis: Clinical Challenges, Patient-Centered Outcomes, and Quality of Life
October 23, 2026 | Location: Exhibit Hall A, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 801 Dialysis: Hemodialysis and Frequent Dialysis
Authors
- Senthilrajan, Ashwin Kumar, University of the Incarnate Word, Laredo, Texas, United States
- Gunturu, Akshay, University of the Incarnate Word, Laredo, Texas, United States
- Saldivar, Klarissa A., University of the Incarnate Word, Laredo, Texas, United States
- Cardenas, Armando Tomas, Laredo Medical Center, Laredo, Texas, United States
- Camacho Mariscal, Rigoberto, University of the Incarnate Word, Laredo, Texas, United States
- Sandhu, Devkarn, University of the Incarnate Word, Laredo, Texas, United States
Group or Team Name
- Hope
Introduction
Ocular disequilibrium syndrome is a rare complication associated with hemodialysis, characterized by ocular discomfort or pain that coincides with dialysis sessions. Disequilibrium syndrome happens due to electrolyte and osmotic changes during dialysis. This case report presents a unique instance of ODS in a patient with ESRD, highlighting the importance of recognizing its symptoms and adjusting dialysis parameters to manage the condition effectively.
Case Description
A 43-year-old male with a medical history of ESRD on HD, hypertension, and glaucoma presented with complaints of weakness, dizziness secondary to not able to complete his outpatient dialysis due to ocular pain. Initial laboratory revealed hyperkalemia, uremia, and metabolic acidosis. The patient reported having undergone ocular surgery one month prior for vitreous hemorrhage and cataract surgery. On presentation, the patient was initiated on HD. During the first session, he experienced eye pain but was able to complete dialysis. In subsequent sessions, the Eye pain recurred, severe enough to necessitate early termination of dialysis. Notably, Discontinuation of dialysis resulted in resolution of ocular pain. Modifications to the dialysis regimen, including adjustments to the sodium bath, and blood flow rate, led to significant improvement. Patient was then able to tolerate dialysis sessions without recurrence of ocular pain leading to the diagnosis of Ocular Disequilibrium syndrome.
Discussion
This case emphasizes the understanding of pathophysiological mechanisms underlying Ocular disequillibrium syndrome, particularly in patients presenting with eye pain after recent ocular surgeries. ODS primarily arises due to rapid shifts in osmotic gradients between the intracellular and extracellular compartments within ocular tissues, especially during hemodialysis. The eye, being an osmotically sensitive organ, relies heavily on the balance of fluid and electrolytes to maintain intraocular pressure and optical clarity. Disruptions in this balance can lead to ocular discomfort and visual disturbances. ODS, though infrequently recognized, can significantly impact patient comfort and continuity of essential therapies like dialysis. The incidence of ODS is decreasing due to early intervention and preventive measures. A deeper exploration of its pathophysiology offers valuable insights into effective diagnosis and management.