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Kidney Week

Abstract: FR-PO1047

National Epidemiology and Survival Analysis of Patients on Dialysis in Thailand Using the TRT Registry

Session Information

Category: Dialysis

  • 801 Dialysis: Hemodialysis and Frequent Dialysis

Authors

  • Satirapoj, Bancha, Phramongkutklao Hospital, Bangkok, Thailand
  • Tantiyavarong, Pichaya, Thammasat University, Bangkok, Thailand
  • Thimachai, Paramat, Phramongkutklao Hospital, Bangkok, Thailand
  • Lumpaopong, Adisorn, Phramongkutklao Hospital, Bangkok, Thailand
  • Kanjanabuch, Talerngsak, Chulalongkorn University, Bangkok, Thailand
  • Ophascharoensuk, Vuddhidej, Chiang Mai University, Chiang Mai, Thailand
Background

End-stage kidney disease (ESKD) poses a major global health burden, including in Thailand, where patients requiring chronic dialysis experience high mortality. The Thailand Renal Replacement Therapy (TRT) Registry provides a comprehensive national database capturing patient characteristics, treatment patterns, and outcomes.

Methods

We conducted a retrospective cohort study using TRT Registry data (2024), including 140,031 chronic hemodialysis patients from 1,206 centers, linked with national mortality records. Survival trends were analyzed.

Results

Diabetes (32.7%) and hypertension (32.2%) were the leading causes of ESKD. Among biopsy-proven glomerulonephritis, IgA nephropathy was most common (28.9%). Thrice-weekly hemodialysis predominated (67.5%), followed by twice-weekly (30.8%). Between 2017 and 2024, 83,344 deaths occurred among 212,612 patients (39.2%), with an overall mortality rate of 9.5 per 100 patient-years. Mortality was higher in peritoneal dialysis than hemodialysis (13.3 vs. 8.8 per 100 patient-years). Cardiovascular disease was the leading cause of death (20.1%), followed by infections (12.7%). Over a median follow-up of 2.48 years, 1-, 3-, and 5-year survival rates were 95.4%, 78.9%, and 61.9%, respectively. Survival differed significantly by ESKD etiology and dialysis frequency (p<0.001). Patients with diabetic nephropathy and those receiving twice-weekly dialysis had the poorest 5-year survival (54.6% and 52.7%), compared with thrice- and four-times-weekly regimens (67.0% and 71.7%).

Conclusion

In Thailand, dialysis outcomes show acceptable short-term survival but substantial long-term mortality. Diabetes and suboptimal dialysis frequency are key determinants of poorer outcomes, highlighting the need for optimized dialysis delivery and targeted risk reduction strategies.

Acknowledgment

The Thailand Renal Replacement Therapy (TRT) Committee would like to express its sincere appreciation to all nephrologists, as well as the staff of dialysis and transplant centers, for their invaluable contributions, and to the Thai Renal Replacement Therapy staff officers for their dedicated support.