Abstract: FR-PO1020
HA130 Hemoperfusion for Refractory Uremic Pruritus in Maintenance Hemodialysis: Experience from Tanzania
Session Information
- Hemodialysis: Clinical Challenges, Patient-Centered Outcomes, and Quality of Life
October 23, 2026 | Location: Exhibit Hall A, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 801 Dialysis: Hemodialysis and Frequent Dialysis
Author
- Meshack, Benjamin Emmanuel, Meditec Systems Ltd, Dar es Salaam, Tanzania, United Republic of
Introduction
Uremic pruritus is a debilitating complication in maintenance hemodialysis patients and may cause severe sleep disturbance and poor quality of life. Conventional therapies often provide limited relief. We report successful management of refractory uremic pruritus using adjunctive HA130 hemoperfusion.
Case Description
A 62-year-old female receiving maintenance hemodialysis presented with severe refractory uremic pruritus for approximately one year despite antihistamines, hydrocortisone injections, and other anti-pruritic medications. Symptoms included severe nocturnal itching, inability to sleep, and repetitive scratching causing skin irritation.
The patient received adjunctive HA130 hemoperfusion combined with maintenance dialysis (HD + HP and HDF + HP). One HA130 hemoperfusion cartridge was administered weekly during 4-hour dialysis sessions for 3 treatments.
Baseline pruritus severity was 10/10 before treatment. Following therapy, symptoms improved to 0–1/10 with improved sleep quality and reduced antihistamine and corticosteroid use. Clinical improvement persisted from February 2024 through January 2026, although mild recurrence occurred during extended follow-up.
Discussion
This case highlights the potential role of adjunctive HA130 hemoperfusion in refractory uremic pruritus among maintenance hemodialysis patients. Treatment was associated with prolonged symptom relief, improved sleep, and reduced dependence on symptomatic medications after failure of conventional therapy.
Acknowledgment
The authors acknowledge the dialysis teams and healthcare professionals involved in patient care and monitoring during hemoperfusion treatment sessions in Tanzania.
Clinical Outcomes Following Adjunctive HA130 Hemoperfusion in Maintenance Hemodialysis Patients With Refractory Uremic Pruritus
| Patient | Severity Before | HA 130 Sessions | Outcome | Follow - up |
| Patient 1 | Severe (10/10) | 3 | Complete relief | Mild recurrence after 24 months |
| Patient 2 | Moderate | 2 | Complete relief | No recurrence |
| Patient 3 | Severe | 4 | Complete relief | No recurrence |