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Abstract: TH-PO1035

BMI Associated with the Risk of Urinary Tract Infections in Immediate Kidney Transplantation

Session Information

Category: Transplantation

  • 2002 Transplantation: Clinical

Authors

  • Cardoso, Ana Lídia Santos, Programa de Pós-Graduação em Microbiologia, Universidade Federal da Bahia, Salvador, Bahia, Brazil
  • Tapioca, Fernanda Martin, Hospital Ana Nery, Salvador, Bahia, Brazil
  • Passos, Luiz Carlos, Hospital Ana Nery, Salvador, Bahia, Brazil
  • Montaño-Castellon, Iris, HEMOBA - Centro de Referência às Pessoas com Doença Falciforme, Salvador, Bahia, Brazil
  • Gutierrez-Peredo, Andrea Jimena, Programa de Pós-Graduação em Medicina e Saúde, Universidade Federal da Bahia, Salvador, Bahia, Brazil
  • Azevedo Guedes, Sammara, Hospital Ana Nery, Salvador, Bahia, Brazil
  • Mattos, Lucas, Hospital Ana Nery, Salvador, Bahia, Brazil
  • Machado, Milena, Hospital Ana Nery, Salvador, Bahia, Brazil
  • Ribeiro, Francine Peixoto Santos, Hospital Ana Nery, Salvador, Bahia, Brazil
  • Soares, Marla Fonseca, Hospital Ana Nery, Salvador, Bahia, Brazil
  • Pita Mendes da Costa, Fernanda, Hospital Ana Nery, Salvador, Bahia, Brazil
  • Tavares de Araújo, Tardelly, Hospital Ana Nery, Salvador, Bahia, Brazil
  • Costa Neves, Felipe, Hospital Ana Nery, Salvador, Bahia, Brazil
  • Lopes, Marcelo, Hospital Ana Nery, Salvador, Bahia, Brazil
  • Mattoso, Ricardo Jose Costa, Hospital Ana Nery, Salvador, Bahia, Brazil
  • Aguilar Ticona, Juan Pablo, Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde, Salvador, Bahia, Brazil
  • Gutierrez Peredo, Gabriel Brayan, Hospital Ana Nery, Salvador, Bahia, Brazil

Group or Team Name

  • Nephro-HAN
Background

Urinary tract infections (UTIs) are the most common complications following kidney transplantation, particularly during the early post transplant period, and are associated with increased morbidity and poorer patient outcomes.

Methods

To determine the prevalence of UTIs and to identify the risk factors associated with their occurrence. We conducted a cross sectional study among kidney transplant recipients in Salvador, Brazil (2021–2023). Early post transplant UTI was defined as infection occurring within the first 3 months after transplantation. Medical records were used to obtain clinical and laboratorial data. Laboratory confirmation included antimicrobial resistance testing. A multivariable logistic regression analysis was performed to identify factors associated with early post transplant UTI, and predicted probabilities were estimated across body mass index (BMI) stratified by sex.

Results

Among 215 kidney transplant recipients, 79 (37%) developed early post-transplant UTI. The main pathogens were Klebsiella pneumoniae (44%) and Escherichia coli (25%), with antimicrobial resistance in over half of isolates (MDR 25%, ESBL 24%, XDR/CRAB 3%). Female sex (OR= 2.4; 95% CI 1.37–4.41) and higher BMI (OR= 1.09; 95% CI 1.02–1.17) were independently associated with increased risk. In the stratified analysis, female sex showed a higher risk of ITU compared to males.

Conclusion

We identified that 37% of kidney transplant recipients developed early post transplant UTIs, frequently caused by resistant pathogens. Higher BMI and female sex were independently associated with increased risk. These findings underscore the importance of early risk stratification, incorporating nutritional status, and highlight women with elevated BMI as a priority group for targeted interventions prior to transplantation.