Abstract: FR-PO1093
Ultraviolet (UV) Flash Device System Is Associated with Lower Incidence of Peritonitis in Patients on Peritoneal Dialysis
Session Information
- Home Dialysis: Modalities, Barriers, Utilization, and Clinical Outcomes
October 23, 2026 | Location: Exhibit Hall A, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 802 Dialysis: Home Dialysis and Peritoneal Dialysis
Authors
- Tsuchimoto, Akihiro, Kyushu Daigaku, Fukuoka, Fukuoka Prefecture, Japan
- Nakano, Toshiaki, Kyushu Daigaku, Fukuoka, Fukuoka Prefecture, Japan
- Tsuneyoshi, Shoji, Kyushu Daigaku, Fukuoka, Fukuoka Prefecture, Japan
- Okamura, Kazuhiro, Kyushu Daigaku, Fukuoka, Fukuoka Prefecture, Japan
- Hamashoji, Tomoya, Kyushu Daigaku, Fukuoka, Fukuoka Prefecture, Japan
- Yamada, Shunsuke, Kyushu Daigaku, Fukuoka, Fukuoka Prefecture, Japan
- Tsuruya, Kazuhiko, Nara Kenritsu Ika Daigaku, Kashihara, Nara Prefecture, Japan
- Ago, Tetsuro, Kyushu Daigaku, Fukuoka, Fukuoka Prefecture, Japan
Background
Peritoneal dialysis (PD) -related peritonitis remains a major cause of technique failure and mortality. The use of the UV flash device system for peritoneal dialysis has been expected to reduce peritonitis; however, the evidence is insufficient. This study aimed to examine whether the UV flash device system Tsunagu reduces peritonitis.
Methods
In this study, 97 patients have used the UV flash device system Tsunagu among 249 patients who underwent PD from 2006 to 2025 in Kyushu University Hospital. After excluding 12 patients who used the other automated connection system, we enrolled 237 patients in this study. The patients were followed until March 2026. We compared the incidence of peritonitis in 97 patients who used the UV flash device system Tsunagu with those in 140 patients who used the manual connection. The incidence of peritonitis was evaluated using Kaplan-Meier analysis and negative binomial regression models.
Results
The incidence of peritonitis in patients of the UV flash device system Tsunagu group was 0.132 times/patient-year, while the incidence of peritonitis in patients of the manual connection group was 0.271 times/patient-year. The risk of first incidence of peritonitis was significantly lower in patients of the Tsunagu group compared to those of the manual connection group (P=0.03, log-rank test). Multivariable analysis showed that the use of the Tsunagu group was significantly associated with a lower incidence of peritonitis compared to the manual connection group (incidence rate ratios 0.72, 95% CI 0.58-0.88, P<0.01). Furthermore, the Tsunagu group showed a significantly lower incidence of peritonitis caused by Gram-positive cocci (P=0.01, log-rank test). Multivariable analysis showed that the Tsunagu group significantly reduced the incidence of peritonitis caused by Gram-positive cocci (incidence rate ratios 0.75, 95% CI 0.67-0.84, P<0.01).
Conclusion
The UV flash device system Tsunagu was associated with a lower incidence of PD-related peritonitis in patients, particularly peritonitis caused by Gram-positive cocci.
Funding
- Private Foundation Support