Abstract: FR-PO1099
Exploration of Symptom Burden During a Wearable Peritoneal Dialysis Device (Viva Kompact) Trial: A Mixed-Method Analysis
Session Information
- Home Dialysis: Modalities, Barriers, Utilization, and Clinical Outcomes
October 23, 2026 | Location: Exhibit Hall A, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 802 Dialysis: Home Dialysis and Peritoneal Dialysis
Authors
- Htay, Htay, Singapore General Hospital, Singapore, Singapore
- Schreiber, Martin J., Cleveland Clinic, Cleveland, Ohio, United States
- Jain, Arsh, London Health Sciences Centre, London, Ontario, Canada
- Brown, Edwina A., Imperial College Healthcare NHS Trust, London, England, United Kingdom
- Gow, Sheena, Vivance Pte Ltd, Singapore, Singapore
- Lim, Jason Tze Chern, Vivance Pte Ltd, Singapore, Singapore
- Gori, Mandar, Vivance Inc, Westlake Village, California, United States
- Foo, Marjorie Wai Yin, Singapore General Hospital, Singapore, Singapore
Background
Symptom burden in peritoneal dialysis (PD) patients is high and multifactorial, partly due to chronic illness from kidney failure and partly related to treatment-associated symptoms from dialysis. Wearable PD systems may alter treatment delivery and fluid dynamics, potentially influencing symptom experience. Symptom frequency, severity, and patient reported experience were evaluated during a pre-pivotal study of a wearable sorbent-based PD system, Viva Kompact (Kompact).
Methods
Participants recorded daily frequency and severity for 23 predefined symptoms during a screening period (while on conventional automated PD) and during a 7-day Kompact therapy period. Semi-structured interviews were conducted to contextualize symptom reports and to provide feedback about their device experience.
Results
Eleven participants who entered the 7-day Kompact treatment phase recorded their PD-related symptoms. Overall, symptoms appeared to be less frequent with Kompact therapy compared with conventional APD therapy (53 vs 88). The majority of symptoms were mild, with only a few reported as severe (Figure 1). Symptoms of pruritus, poor sleep, and drain pain appeared to improve following initiation of Kompact PD therapy (Figure 2). During interviews, some participants reported positive feedback regarding abdominal pain, drain pain, and sleep quality while on Kompact PD therapy (Table 1).
Conclusion
Participants experienced less symptoms during the intervention period, however due to the small sample size and short duration, conclusion of device superiority in symptomology needs further investigation.
Funding
- Commercial Support – Vivance Pte Ltd