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Kidney Week

Abstract: FR-PO0407

Effect of Atherogenic Index of Plasma on Risk of Contrast-induced AKI: An In-Hospital Electronic Monitoring System

Session Information

Category: Acute Kidney Injury

  • 102 AKI: Clinical, Outcomes, and Trials

Authors

  • Xu, Youjun, Ningbo No 2 Hospital, Ningbo, Zhejiang, China
  • Zheng, Xingyue, Ningbo No 2 Hospital, Ningbo, Zhejiang, China
  • Zhou, Fangfang, Ningbo No 2 Hospital, Ningbo, Zhejiang, China
  • Luo, Qun, Ningbo No 2 Hospital, Ningbo, Zhejiang, China
Background

This study focuses on exploring the association between atherogenic index of plasma (AIP) and contrast-induced acute kidney injury (CI-AKI).

Methods

This study was carried out using the data from the in-hospital electronic monitoring system from June 1 2019 to July 31 2025 at Ningbo No. 2 Hospital, Zhejiang province, China. The association between AIP and CI-AKI was analyzed using logistic regression and restricted cubic spline (RCS) regression.

Results

The study included a total of 4220 patients, with 350 (8.29%) developed CI-AKI. The average age was 66.35±13.35 years. Table 1 showed that in the multivariate logistic regression analysis, after adjusting for confounding factors, AIP remained an independent risk factor for CI-AKI (OR=2.70, 95%CI=1.74-4.19,P<0.001). RCS regression analysis displayed that AIP demonstrated a linear relationship with CI-AKI (P<0.001, P for nonlinear=0.844) in figure 1.

Conclusion

The risk of CI-AKI occurrence was linearly related to AIP, highlighting the importance of monitoring AIP in clinical practice.

Table 1. Logistic regression analysis
ModelOR95% CIP
Unadjusted3.872.65-5.66<0.001
Model 14.382.98-6.43<0.001
Model 23.962.63-5.97<0.001
Model 32.701.74-4.19<0.001

Model 1 adjusted for age, gender, and Body Mass Index Model 2 adjusts for age, gender, Body Mass Index, hypertension, diabetes, nephrotoxic antibiotics, vasoactive drugs, diuretics, and statins. Model 3 adjusts for age, gender, Body Mass Index, hypertension, diabetes, nephrotoxic antibiotics, vasoactive drugs, diuretics, statins, white blood cells, hematocrit, C-reactive protein, aspartate aminotransferase, serum creatinine, glucose, and Creatine Kinase MB.

Fig 1. Associations between AIP and CI-AKI in restricted cubic spline regression