Abstract: TH-PO0894
Changes in Physical Performance Before and After Dialysate Infusion in Patients on Peritoneal Dialysis
Session Information
- Home Dialysis: Utilization Patterns, Complications, and Quality-of-Life Outcomes
October 22, 2026 | Location: Exhibit Hall A, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 802 Dialysis: Home Dialysis and Peritoneal Dialysis
Authors
- Choi, Hae Dong, Yeungnam University Medical Center, Daegu, Korea (the Republic of)
- Do, Jun-Young, Yeungnam University Medical Center, Daegu, Korea (the Republic of)
- Park, Jong-Won, Yeungnam University Medical Center, Daegu, Korea (the Republic of)
- Cho, Kyu-hyang, Yeungnam University Medical Center, Daegu, Korea (the Republic of)
- Kang, Seok hui, Yeungnam University Medical Center, Daegu, Korea (the Republic of)
- Kim, A Young, Yeungnam University Medical Center, Daegu, Korea (the Republic of)
Background
Adequate solute clearance and volume control during peritoneal dialysis (PD) require sufficient intraperitoneal dialysate volume, yet concerns remain that dialysate load may impair physical performance or worsen sarcopenia. We evaluated changes in physical performance and sarcopenia-related parameters before and after intraperitoneal dialysate infusion.
Methods
In this retrospective, single-center study, 30 outpatients with end-stage renal disease undergoing PD were evaluated during routine visits under two conditions: with 2L daytime dialysate in the peritoneal cavity and after complete drainage. Physical performance was assessed using the Short Physical Performance Battery (SPPB), 4-meter gait speed, five-times sit-to-stand, balance tests, Timed Up and Go (TUG) test, and handgrip strength. Skeletal muscle index was measured by bioelectrical impedance analysis. Sarcopenia was defined according to the Asian Working Group for Sarcopenia 2025 criteria. Paired comparisons were performed using the Wilcoxon signed-rank test.
Results
After dialysate drainage, total SPPB score improved modestly but significantly, primarily driven by increased gait speed, and chair-stand time decreased. Balance, handgrip strength, and TUG did not change significantly. Muscle strength and muscle mass indices, as well as sarcopenia prevalence, remained stable before and after dialysate infusion. Similar findings were observed across subgroups, including continuous ambulatory PD (CAPD) and automated peritoneal dialysis (APD).
Conclusion
Intraperitoneal dialysate infusion was not associated with clinically meaningful deterioration in physical performance or sarcopenia status. Although gait speed and SPPB improved after drainage, overall sarcopenia-related indicators were unchanged. These findings support the feasibility of prescribing adequate dialysate volumes when clinically indicated without major concern for functional decline.